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[T-激活素在急性化脓性肾盂肾炎患者联合治疗中的临床免疫效应]

[The clinico-immunological effects of T-activin in the combined treatment of patients with acute suppurative pyelonephritis].

作者信息

Vozianov A F, Drannik G N, Pasechnikov S P, Driianskaia V E, Petrovskaia I A, Kushko L Ia, Ozvinchuk I I, Potrebinskiĭ V M, Milinevskiĭ V A

出版信息

Lik Sprava. 1995 Sep-Dec(9-12):81-3.

PMID:8983802
Abstract

Results were studied of use of T-activin in those clinical settings related to acute inflammatory diseases of the kidneys. There was a positive clinical effect from this preparation in all twenty-eight patients with acute purulent pyelonephritis, accompanied by readjustments in the patients' immune system. A rise to the norm was found to occur in T-helper counts, and accordingly, immunoregulatory index, NK-cell activity, blood microbocydic activity. The in vitro investigations done suggested the need for individual testing of immunocompetent cells of the patient to optimize the therapy.

摘要

研究了T-激活素在与肾脏急性炎症性疾病相关的临床环境中的使用结果。在所有28例急性化脓性肾盂肾炎患者中,该制剂产生了积极的临床效果,并伴有患者免疫系统的调整。发现辅助性T细胞计数、免疫调节指数、自然杀伤细胞活性和血液杀菌活性均恢复到正常水平。体外研究表明,需要对患者的免疫活性细胞进行个体检测,以优化治疗。

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