Arntz H R
Kardiopulmonologie, Charité, Campus Benjamin Franklin, Hindenburgdamm 30, Berlin, Germany.
Internist (Berl). 2008 Sep;49(9):1023-30. doi: 10.1007/s00108-008-2073-4.
The time period from symptom onset to hospital admission is of outstanding importance for the prognosis of a patient with an acute myocardial infarction. He is threatened by sudden cardiac death triggered by ventricular fibrillation on the one hand and on the other hand this period offers the chance for a timely decision on the optimal reperfusion strategy. A broad spectrum of therapeutic opportunities regarding thrombolysis, antiplatelets and anticoagulation has been proven to be effective in large randomised trials and registries. These results should influence the individual decision on reperfusion treatment as well as the patient's conditions, time lines, logistics and local resources.
从症状出现到入院的时间段对于急性心肌梗死患者的预后极为重要。一方面,患者受到心室颤动引发的心源性猝死的威胁;另一方面,这段时间为及时决定最佳再灌注策略提供了机会。关于溶栓、抗血小板和抗凝的广泛治疗机会已在大型随机试验和登记研究中被证明是有效的。这些结果应影响再灌注治疗的个体决策以及患者的病情、时间安排、后勤保障和当地资源。