从华南楠树皮中提取的新原阿朴啡类生物碱。

New proaporphines from the bark of Phoebe scortechinii.

作者信息

Mukhtar Mat Ropi, Hadi A Hamid A, Rondeau David, Richomme Pascal, Litaudon Marc, Mustafa M Rais, Awang Khalijah

机构信息

Faculty of Science, Department of Chemistry, University of Malaya, 50603 Kuala Lumpur, Malaysia.

出版信息

Nat Prod Res. 2008;22(11):921-6. doi: 10.1080/14786410701642821.

DOI:10.1080/14786410701642821

PMID:18629705

Abstract

The phytochemical study of the bark of Malaysian Phoebe scortechinii (Lauraceae) has resulted in the isolation and identification of two new proaporphine alkaloids; (+)-scortechiniine A (1) and (+)-scortechiniine B (2) together with two known proaporphines; (-)-hexahydromecambrine A (3), (-)-norhexahydromecambrine A (4), and one aporphine; norboldine (5). Structural elucidations of these alkaloids were performed using spectroscopic methods especially 1D and 2D (1)H and (13)C NMR.

摘要

对马来西亚楠木（樟科）树皮进行的植物化学研究，已分离并鉴定出两种新的原阿朴啡生物碱；（+）-斯科泰奇宁A（1）和（+）-斯科泰奇宁B（2），以及两种已知的原阿朴啡生物碱；（-）-六氢新防己碱A（3）、（-）-去甲六氢新防己碱A（4）和一种阿朴啡生物碱；去甲波尔定（5）。这些生物碱的结构解析采用了光谱方法，尤其是一维和二维（1）H和（13）C核磁共振谱。