[不同强度脉冲电磁场对去卵巢大鼠血清雌二醇的影响]
[Effects of different intensity pulsed electromagnetic fields on serum estradiol of ovariectomized rats].
作者信息
Yang Yong-Hong, He Cheng-Qia, Yang Lin, Wang Wei, Lei Zhong-Jie
机构信息
Department of Rehabilitation, West China Hospital, Sichuan University, Chengdu 610041, China.
出版信息
Sichuan Da Xue Xue Bao Yi Xue Ban. 2008 Mar;39(2):256-8.
OBJECTIVE
To explore the effects of different intensity pulsed electromagnetic fields (PEMFs) on serum estradiol in ovariectomized rats.
METHODS
Fifty female SD rats were randomly divided into five groups: sham-operated control (no PEMF treatment), ovariectomized control(no PEMF treatment),ovariectomized group I, II, III (PEMF treatment at 8 Hz frequency and 0.77 mT, 3.82 mT, 9.87 mT intensity, 40 min daily for 30 days). Except for the sham-operated control rats, a standardized ovariectomy was used on every rat of other groups. The serum estradiol(E2) of rats was assessed at 30 days after PEMF treatment.
RESULTS
The E2 values of the SHAM control group were significantly higher than those of other four groups (P < 0.05 or P < 0.01), but the difference in E2 values was not significant among the other four groups (P > 0.05).
CONCLUSION
PEMFs can not improve the serum estradiol level of ovariectomized rat, it shows that the therapeutical effect of PEMFs is not due to improve the serum estradiol level.
目的
探讨不同强度脉冲电磁场（PEMFs）对去卵巢大鼠血清雌二醇的影响。
方法
将50只雌性SD大鼠随机分为五组：假手术对照组（未进行PEMF治疗）、去卵巢对照组（未进行PEMF治疗）、去卵巢I组、II组、III组（8 Hz频率、0.77 mT、3.82 mT、9.87 mT强度的PEMF治疗，每天40分钟，共30天）。除假手术对照组大鼠外，其他组的每只大鼠均采用标准化去卵巢手术。在PEMF治疗30天后评估大鼠血清雌二醇（E2）水平。
结果
假手术对照组的E2值显著高于其他四组（P < 0.05或P < 0.01），但其他四组之间E2值的差异不显著（P > 0.05）。
结论
PEMFs不能提高去卵巢大鼠的血清雌二醇水平，表明PEMFs的治疗效果不是由于提高血清雌二醇水平所致。
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