Raphaël Jean-Claude
Service de réanimation médico-chirurgicale, hôpital Raymond-Poincaré, 92380 Garches.
Rev Prat. 2008 Apr 30;58(8):849-54.
Carbon monoxide (CO) poisoning is still complicated by a high mortality and morbidity rate. Diagnosis can be obvious but is most of time difficult and sometimes remained unknown. It is usually based on clinical signs and must be confirmed by assessment of CO level in room air or in patient's expired breathing or blood and detection of a source. Mild neurological sequelae are very common. Normobaric oxygen is the first line treatment. Comatose and pregnant patients must undergo hyperbaric oxygen. All CO poisoning has to be declared to sanitary authority, which will in turn conduct a technical inspection to remove the source. The patient must be informed that he is at risk of new poisoning and of neurological complications. Progress in prevention and research in therapeutics are needed in order to reduce CO related morbidity.
一氧化碳（CO）中毒的死亡率和发病率仍然很高，情况复杂。诊断有时显而易见，但多数时候很难，甚至有时无法确诊。诊断通常基于临床症状，必须通过评估室内空气、患者呼出气体或血液中的CO水平并检测来源来确认。轻度神经后遗症非常常见。常压氧是一线治疗方法。昏迷患者和孕妇必须接受高压氧治疗。所有CO中毒病例都必须上报卫生部门，卫生部门会进行技术检查以消除中毒源。必须告知患者有再次中毒和出现神经并发症的风险。为降低与CO相关的发病率，需要在预防和治疗研究方面取得进展。
