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肺循环中的心脏外带瓣管道。

Extracardiac valved conduits in the pulmonary circuit.

作者信息

Sano S, Karl T R, Mee R B

机构信息

Victorian Paediatric Cardiac Surgical Unit, Royal Children's Hospital, Melbourne, Australia.

出版信息

Ann Thorac Surg. 1991 Aug;52(2):285-90. doi: 10.1016/0003-4975(91)91354-x.

Abstract

Extracardiac valved conduits represent one of the weakest facets of reconstructive surgery for congenital heart disease in that they invariably need to be replaced because of growth of the patient or because of valve or conduit failure. Between 1979 and 1989, 141 patients had 169 valved conduits placed between the heart and the pulmonary artery circuit. There were 81 male and 60 female patients, aged 2 days to 35 years (mean age, 5.9 years), with 46 patients less than 1 year of age. We performed primary repair in 117 patients; in this group, there have been 28 conduit replacements in 27 patients. In 17 patients initial repair with a conduit was performed elsewhere and we replaced these conduits in 15 and removed them in 2. A further group of 9 patients were seen after repair of tetralogy of Fallot or double-outlet right ventricle, with severe pulmonary incompetence or right ventricular outflow tract aneurysm. All had valved conduits inserted as secondary procedures. The types of valved conduits used were xenograft (n = 126) and homograft (n = 43). There were six hospital deaths (3.6%; 70% confidence limits [CL], 2% to 6%) and seven late deaths (4.1%; CL, 2.5% to 6.5%) in a total of 169 conduit insertions. Forty-five conduits have been removed and 43 reinserted without early or late mortality (0%; CL, 0% to 4%). Actuarial survival after conduit insertion was 87% at 5 years (CL, 80% to 92%), including operative mortality. Actuarial freedom from conduit replacement was 37% at 5 years (CL, 20% to 56%). Conduit insertion in infants and small children ensures subsequent replacement, but this can be done at low risk.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

心外带瓣管道是先天性心脏病重建手术中最薄弱的环节之一,因为随着患者生长或由于瓣膜或管道功能衰竭,它们总是需要更换。1979年至1989年期间,141例患者在心脏与肺动脉循环之间植入了169根带瓣管道。有81例男性和60例女性患者,年龄从2天至35岁(平均年龄5.9岁),其中46例患者年龄小于1岁。我们对117例患者进行了一期修复;在该组中,27例患者进行了28次管道置换。17例患者最初在其他地方进行了带管道的修复,我们对其中15例患者的管道进行了置换,2例患者的管道被移除。另有9例患者在法洛四联症或右心室双出口修复术后就诊,伴有严重的肺动脉瓣关闭不全或右心室流出道动脉瘤。所有患者均作为二期手术植入了带瓣管道。所用带瓣管道的类型为异种移植物(n = 126)和同种移植物(n = 43)。在总共169次管道植入中,有6例医院死亡(3.6%;70%置信区间[CL],2%至6%)和7例晚期死亡(4.1%;CL,2.5%至6.5%)。45根管道已被移除,43根管道在无早期或晚期死亡的情况下重新植入(0%;CL,0%至4%)。包括手术死亡率在内,管道植入后的5年精算生存率为87%(CL,80%至92%)。5年时无需更换管道的精算自由度为37%(CL,20%至56%)。在婴儿和幼儿中植入管道可确保后续进行更换,但风险较低。(摘要截取自250个单词)

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