Rubino Annalisa, Rousculp Matthew D, Davis Kimberly, Wang Jianmin, Bastyr Edward J, Tesfaye Solomon
RTI Health Solutions, Manchester Science Park, Manchester, UK.
Prim Care Diabetes. 2007 Sep;1(3):129-34. doi: 10.1016/j.pcd.2007.07.006. Epub 2007 Aug 17.
The objective of this study was to describe the proportion and characteristics of patients with type 1 and type 2 diabetes diagnosed with diabetic peripheral neuropathy (DPN) in France, Italy, Spain, and the United Kingdom (UK).
A cross-sectional survey was administered to general practitioners and diabetes specialists. Existing physicians' records were used to quantify the frequency of DPN diagnoses, and notes from patients' medical charts were used to characterize symptoms.
The average number of physicians per country was 41 (range of 34-49). The proportion of diabetes patients diagnosed with DPN ranged from 9.6% (95% CI, 7.1-12.2) in Spain to 23.1% (95% CI, 15.4-30.7) in Italy. Of 913 DPN study patients, 55.0% were male, and 78.5% had type 2 diabetes. Mean age was 64.5+/-12.5 years. A DPN diagnosis was based primarily on symptoms. Approximately 27% of patients had no documented neurological examination. "Prickling" was the most common DPN symptom recorded in France, Italy, and Spain, and "numbness" was the most common in the UK.
Country-specific estimates of DPN diagnosis may reflect clinical management of diabetes and DPN. A substantial number of diagnoses were not associated with a record of a neurological examination.
本研究的目的是描述在法国、意大利、西班牙和英国被诊断为糖尿病周围神经病变(DPN)的1型和2型糖尿病患者的比例及特征。
对全科医生和糖尿病专科医生进行了一项横断面调查。利用现有的医生记录来量化DPN诊断的频率,并使用患者病历中的记录来描述症状。
每个国家的医生平均人数为41名(范围为34 - 49名)。被诊断为DPN的糖尿病患者比例从西班牙的9.6%(95%置信区间,7.1 - 12.2)到意大利的23.1%(95%置信区间,15.4 - 30.7)不等。在913名DPN研究患者中,55.0%为男性,78.5%患有2型糖尿病。平均年龄为64.5±12.5岁。DPN诊断主要基于症状。约27%的患者没有记录在案的神经学检查。“刺痛”是法国、意大利和西班牙记录的最常见的DPN症状,而“麻木”在英国最为常见。
特定国家的DPN诊断估计值可能反映了糖尿病和DPN的临床管理情况。相当数量的诊断与神经学检查记录无关。