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吡喹酮治疗神经囊尾蚴病:长期随访

Praziquantel in the treatment of neurocysticercosis: long-term follow-up.

作者信息

Sotelo J, Torres B, Rubio-Donnadieu F, Escobedo F, Rodriguez-Carbajal J

出版信息

Neurology. 1985 May;35(5):752-5. doi: 10.1212/wnl.35.5.752.

DOI:10.1212/wnl.35.5.752
PMID:3990975
Abstract

Thirty-five patients with active neurocysticercosis were treated with praziquantel and followed for 1 year after therapy. CT and CSF analysis showed that 91% of patients with parenchymal cysts improved, and 47% of patients with chronic arachnoiditis had remission. A single treatment with praziquantel for 2 weeks, administered in a daily dose of 50 mg/kg of body weight, was highly effective in parenchymal cysticercosis but less effective in meningeal cysticercosis. The benefits were sustained for at least 1 year.

摘要

35例活动性神经囊尾蚴病患者接受了吡喹酮治疗,并在治疗后随访1年。CT和脑脊液分析显示,91%的实质囊肿患者病情改善,47%的慢性蛛网膜炎患者病情缓解。吡喹酮单次治疗2周,每日剂量为50mg/kg体重,对实质型囊尾蚴病高度有效,但对脑膜型囊尾蚴病效果较差。疗效至少持续1年。

相似文献

1
Praziquantel in the treatment of neurocysticercosis: long-term follow-up.吡喹酮治疗神经囊尾蚴病:长期随访
Neurology. 1985 May;35(5):752-5. doi: 10.1212/wnl.35.5.752.
2
Therapy of parenchymal brain cysticercosis with praziquantel.吡喹酮治疗脑实质型囊尾蚴病
N Engl J Med. 1984 Apr 19;310(16):1001-7. doi: 10.1056/NEJM198404193101601.
3
Albendazole therapy for neurocysticercosis.阿苯达唑治疗神经囊尾蚴病。
Arch Intern Med. 1987 Apr;147(4):738-41.
4
Early CT reevaluation after empiric praziquantel therapy in neurocysticercosis.
Neurology. 1989 May;39(5):739-41. doi: 10.1212/wnl.39.5.739.
5
[Treatment of cysticercosis using praziquantel. Preliminary report of 10 cases].[使用吡喹酮治疗囊尾蚴病。10例初步报告]
Gac Med Mex. 1983 Jan;119(1):17-22.
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Subcutaneous and cerebral cysticercosis treated with praziquantel.用吡喹酮治疗皮下及脑囊尾蚴病。
Southeast Asian J Trop Med Public Health. 1984 Jun;15(2):201-5.
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[Changes in computerized axial tomography of the skull in cerebral cysticercosis before and after praziquantel therapy].[吡喹酮治疗前后脑囊尾蚴病患者头颅计算机断层扫描的变化]
Salud Publica Mex. 1982 Nov-Dec;24(6):637-41.
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Cerebral cysticercosis treated biphasically with dexamethasone and praziquantel.采用地塞米松和吡喹酮双相治疗脑囊尾蚴病。
Ann Intern Med. 1983 Aug;99(2):179-81. doi: 10.7326/0003-4819-99-2-179.
9
Neurocysticercosis treated with praziquantel. Long-term follow-up of a case.
J Neurosurg Sci. 1991 Jul-Sep;35(3):157-60.
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[Neurocysticercosis and praziquantel: long-term development in 100 patients].[神经囊尾蚴病与吡喹酮:100例患者的长期发展情况]
Arq Neuropsiquiatr. 1989 Dec;47(4):444-8. doi: 10.1590/s0004-282x1989000400010.

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Ther Adv Neurol Disord. 2011 Mar;4(2):67-81. doi: 10.1177/1756285610395654.
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Indian J Pediatr. 2003 Apr;70(4):337-42. doi: 10.1007/BF02723590.
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High-dose praziquantel with cimetidine for refractory neurocysticercosis: a case report with clinical and MRI follow-up.大剂量吡喹酮联合西咪替丁治疗难治性神经囊尾蚴病:1例临床及MRI随访病例报告
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