Metodiewa D, Dunford H B
Department of Chemistry, University of Alberta, Edmonton, Canada.
Biochem Int. 1991 Jan;23(1):183-91.
The peroxidase-catalyzed degradation of 5-hydroxytryptamine (serotonin) was studied using rapid scan or conventional spectrophotometry for detection of one-electron conversions of enzyme compounds I, II and III. The spectral changes of serotonin during oxidation and spectral and bleaching properties of reaction products were examined. The results of the investigation clearly indicate the ability of serotonin to function as an electron donor substrate for animal peroxidases.