Jagannathan Naranamangalam R, Kumar Virendra, Kumar Rajeev, Thulkar Sanjay
Department of NMR, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India.
MAGMA. 2008 Nov;21(6):393-407. doi: 10.1007/s10334-008-0122-6. Epub 2008 Jul 17.
The challenges in detection, localization, and staging of prostate cancer have prompted the investigation of the role of various magnetic resonance (MR) methodologies in a large cohort of men prior to biopsy. The identification of suspicious areas of malignancy was carried out using magnetic resonance imaging (MRI), magnetic resonance spectroscopic imaging (MRSI) and diffusion-weighted imaging (DWI). Our data shows that apparent diffusion coefficient (ADC) may be a reliable marker to differentiate normal, benign, and malignant prostate tissues similar to the metabolite ratio. Also, the combined use of MRSI and DWI improves the diagnosis of prostate cancer. In this review, we present our experience on the use of MRI, MRSI and DWI methods in the assessment of prostate cancer in Indian men. Further, analysis of the comparison of the ADC and the metabolite ratio values reported in the literature across various patient populations are presented.
前列腺癌在检测、定位和分期方面面临的挑战促使人们在一大群男性活检前研究各种磁共振（MR）方法的作用。利用磁共振成像（MRI）、磁共振波谱成像（MRSI）和扩散加权成像（DWI）来识别可疑的恶性区域。我们的数据表明，表观扩散系数（ADC）可能是一种可靠的标志物，可用于区分正常、良性和恶性前列腺组织，类似于代谢物比率。此外，MRSI和DWI的联合使用可提高前列腺癌的诊断水平。在本综述中，我们介绍了在印度男性中使用MRI、MRSI和DWI方法评估前列腺癌的经验。此外，还对文献中报道的不同患者群体的ADC值和代谢物比率值进行了比较分析。
