前列腺癌的扩散加权磁共振成像——单次激发快速自旋回波与回波平面成像序列的比较
Diffusion-weighted MRI in prostate cancer -- comparison between single-shot fast spin echo and echo planar imaging sequences.
作者信息
Kozlowski Piotr, Chang Silvia D, Goldenberg S Larry
机构信息
Prostate Centre at Vancouver General Hospital, Vancouver, British Columbia, Canada V6H 3Z6.
出版信息
Magn Reson Imaging. 2008 Jan;26(1):72-6. doi: 10.1016/j.mri.2007.04.008. Epub 2007 Jun 13.
Diffusion-weighted (DW) MRI at 1.5 T was carried out in two groups of patients. MRI data were correlated with the biopsy and histopathology (where available). The performance of two sequences -- a single-shot FSE (14 patients) and a single-shot EPI (15 patients) -- was compared. Average ADC values from the normal peripheral zone (PZ), central gland (CG) and the tumour [prostate carcinoma (PCa)] were calculated from b values of 0 and 600. Tukey-Kramer test was used for statistical analysis. EPI produced higher values of ADC (10(-3) mm(2)/s) than FSE sequence: 1.992+/-0.208 vs. 1.573+/-0.270 in PZ (P<.001), 1.518+/-0.126 vs. 1.373+/-0.179 in CG and 1.214+/-0.254 vs. 0.993+/-0.158 in PCa (P<.01). In conclusion, both EPI and FSE sequences showed differences in ADC between normal PZ, CG and PCa; however, EPI produced significantly higher ADC values than FSE.
对两组患者进行了1.5T的扩散加权（DW）磁共振成像检查。磁共振成像数据与活检及组织病理学结果（若有）进行了关联。比较了两种序列——单次激发快速自旋回波序列（14例患者）和单次激发回波平面成像序列（15例患者）的性能。根据b值为0和600时的数据计算正常外周带（PZ）、中央腺体（CG）及肿瘤[前列腺癌（PCa）]的平均表观扩散系数（ADC）值。采用Tukey-Kramer检验进行统计学分析。回波平面成像序列产生的ADC值（10⁻³mm²/s）高于快速自旋回波序列：外周带中分别为1.992±0.208和1.573±0.270（P<0.001），中央腺体中分别为1.518±0.126和1.373±0.179，前列腺癌中分别为1.214±0.254和0.993±0.158（P<0.01）。总之，回波平面成像序列和快速自旋回波序列均显示正常外周带、中央腺体及前列腺癌之间的ADC存在差异；然而，回波平面成像序列产生的ADC值显著高于快速自旋回波序列。
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