Olah Laszlo, Borbas Lajos
Polymer Competence Center, Austria.
Acta Bioeng Biomech. 2008;10(1):61-6.
Bone grafting in skeletal reconstruction has become a common task of orthopedic surgeon. Three-dimensional, porous, degradable scaffolds are often used to provide support while the new tissue can be formed in situ. There are numerous materials and techniques involved; however, each has certain drawbacks. One of the patented ceramic bone grafts is made of coral that has many benefits, e.g., its chemical and surface structure similar to that of the cancellous bone, extremely good biocompatibility and optimal pore-size. The drawback, being difficult to overcome, is the manufacturing to the desired shape. In order to maintain the advantageous chemical composition, but to overcome these difficulties, we have manufactured polymer-ceramic scaffolds both by solvent casting and by melt mixing and particulate leaching. The scaffold morphology was examined using scanning electron microscope (SEM), while the compressive properties were chosen to validate these substrates mechanically.
骨骼重建中的骨移植已成为骨科医生的一项常见任务。三维、多孔、可降解的支架常用于提供支撑，同时新组织可在原位形成。这涉及到众多材料和技术；然而，每种都有一定的缺点。一种获得专利的陶瓷骨移植材料由珊瑚制成，它有许多优点，例如其化学和表面结构与松质骨相似、生物相容性极佳且孔径适宜。难以克服的缺点是难以制成所需形状。为了保持有利的化学成分，但又克服这些困难，我们通过溶剂浇铸、熔融混合和颗粒沥滤法制造了聚合物 - 陶瓷支架。使用扫描电子显微镜（SEM）检查支架形态，同时选择压缩性能来从力学角度验证这些基质。
