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在孕期和哺乳期由喂食低脂饮食的母鼠哺育的幼鼠,其脂肪摄入量高于由喂食对照饮食和高脂饮食的母鼠哺育的幼鼠。

Preferential fat intake of pups nursed by dams fed low fat diet during pregnancy and lactation is higher than that of pups nursed by dams fed control diet and high fat diet.

作者信息

Nakashima Yoko, Tsukita Yoko, Yokoyama Meiko

机构信息

Department of Human Nutrition, Seitoku University, Matsudo, Chiba, Japan.

出版信息

J Nutr Sci Vitaminol (Tokyo). 2008 Jun;54(3):215-22. doi: 10.3177/jnsv.54.215.

DOI:10.3177/jnsv.54.215
PMID:18635908
Abstract

To investigate the effect of dams' dietary fat type during pregnancy and lactation on fat choice of pups, three groups of dams were fed one of three diets: a low fat diet (LFD), a control diet (CTD) or a high fat diet (HFD). After weaning their pups were offered a self-selection regimen of both a fat protein diet (FPD) and a carbohydrate protein diet (CPD) for 3 wk. Although the ratio of FPD intake [FPD intake (g)/total intake (g)] by pups nursed by dams fed LFD during the self-selection period was higher than that by pups nursed by dams fed CTD and HFD, no significant difference in the ratio was observed between pups nursed by dams fed CTD and HFD. It was considered that pups nursed by dams fed CTD and HFD self-selected FPD and CPD in an adequate fat energy ratio (F ratio) compared to that of AIN-93G and AIN-93M. The ratio of FPD intake by pups of these three groups was 16-21% within the first week after weaning. Although pups nursed by dams fed CTD continued to consume the same ratio of FPD during the self-selection period, the ratio of pups nursed by dams fed LFD increased and that of pups nursed by dams fed HFD decreased. These findings indicate that: [1] pups nursed by dams fed CTD and HFD have the ability to consume FPD and CPD in an adequate F ratio, and [2] preferential fat intake of pups nursed by dams fed LFD is stronger than that of pups nursed by dams fed CTD and HFD.

摘要

为研究孕期和哺乳期母鼠的饮食脂肪类型对幼鼠脂肪选择的影响,将三组母鼠分别喂食三种饮食之一:低脂饮食(LFD)、对照饮食(CTD)或高脂饮食(HFD)。幼鼠断奶后,为其提供脂肪蛋白质饮食(FPD)和碳水化合物蛋白质饮食(CPD)的自选方案,持续3周。虽然在自选期由喂食LFD的母鼠哺育的幼鼠摄入FPD的比例[FPD摄入量(克)/总摄入量(克)]高于由喂食CTD和HFD的母鼠哺育的幼鼠,但在由喂食CTD和HFD的母鼠哺育的幼鼠之间,该比例未观察到显著差异。据认为,与AIN-93G和AIN-93M相比,由喂食CTD和HFD的母鼠哺育的幼鼠以适当的脂肪能量比(F比)自选FPD和CPD。这三组幼鼠在断奶后的第一周内,FPD摄入量的比例为16 - 21%。虽然在自选期由喂食CTD的母鼠哺育的幼鼠继续消耗相同比例的FPD,但由喂食LFD的母鼠哺育的幼鼠的比例增加,而由喂食HFD的母鼠哺育的幼鼠的比例下降。这些发现表明:[1]由喂食CTD和HFD的母鼠哺育的幼鼠有能力以适当的F比消耗FPD和CPD,并且[2]由喂食LFD的母鼠哺育的幼鼠的优先脂肪摄入量比由喂食CTD和HFD的母鼠哺育的幼鼠更强。

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