Andreu A, Xairó D
Servicio de Microbiología, Ciutat Sanitària Vall d'Hebron, Universidad Autónoma de Barcelona.
Enferm Infecc Microbiol Clin. 1991 Mar;9(3):162-4.
A new method of urine screening based on the enzymatic study of catalase (Uriscreen) was evaluated. Catalase is produced by the majority of microorganisms that cause urinary infections as well as by red cells, uroepithelial cells and PMN. In 553 consecutive urine samples we studied the sediment, the conventional culture, and the Uriscreen test. Comparative study between culture and Uriscreen revealed a sensitivity of 92.3%, specificity of 83.3%, negative predictive value of 96.2%, and positive predictive value of 69.9%. In 86% of the samples the results obtained with both techniques were similar, whereas in 14% of the cases they failed to coincide. Among the 74 cases of disagreement, 12 were false negative (culture positive, Uriscreen negative) and 62 were false positive (culture negative, Uriscreen positive). The high sensitivity and negative predictive values obtained with the screening method indicate that this is an useful procedure for the study of negative urines since it allows to rapidly classify 60.2% of the samples.
对一种基于过氧化氢酶酶学研究的新型尿液筛查方法（尿筛检）进行了评估。大多数引起尿路感染的微生物以及红细胞、尿上皮细胞和多形核白细胞都会产生过氧化氢酶。在553份连续的尿液样本中，我们研究了沉淀物、传统培养以及尿筛检试验。培养与尿筛检之间的对比研究显示，其敏感性为92.3%，特异性为83.3%，阴性预测值为96.2%，阳性预测值为69.9%。在86%的样本中，两种技术获得的结果相似，而在14%的病例中，结果不一致。在74例结果不一致的病例中，12例为假阴性（培养阳性，尿筛检阴性），62例为假阳性（培养阴性，尿筛检阳性）。筛查方法获得的高敏感性和阴性预测值表明，这是一种用于研究阴性尿液的有用方法，因为它能快速对60.2%的样本进行分类。
