Kjellstrand Carl M, Kjellstrand Per
Loyola University Chicago, Chicago, Illinois, USA.
Hemodial Int. 2008 Jul;12 Suppl 1:S33-9. doi: 10.1111/j.1542-4758.2008.00293.x.
Daily home hemodialysis (HD) patients have a much superior survival rate than patients on regular, 3 times a week in-center HD or on peritoneal dialysis. Present-day HD machines are unsuitable for use at home by patients. We present our concept of the ideal home HD machine that allows daily short and long HD, does all the work preparing for and cleaning up after dialysis, has an intravenous infusion system controlled by the patient, needs no systemic anticoagulation, and teaches and interacts with the patient during dialysis. To fulfill these functionalities, the dialyzer and blood tubing must be integrated with the machine and replaced less often than monthly, the machine must be capable of at least 200 L/week of hemodiafiltration, prepare all fluids necessary between and during dialyses, and all the components and fluids must be much beyond ultrapure.
每日家庭血液透析（HD）患者的生存率比接受常规每周3次的中心血液透析或腹膜透析的患者要高得多。目前的血液透析机不适合患者在家中使用。我们提出了理想的家庭血液透析机的概念，该机器允许进行每日短时间和长时间的血液透析，能完成透析前的所有准备工作以及透析后的清理工作，具备由患者控制的静脉输液系统，无需全身抗凝，并且在透析过程中能对患者进行指导和互动。为实现这些功能，透析器和血路管必须与机器集成，且更换频率低于每月一次，机器必须能够每周至少进行200升的血液滤过，准备透析期间及透析之间所需的所有液体，并且所有组件和液体必须远远超过超纯标准。
