Baylor College of Medicine, Divison of Plastic Surgery, 1709 Dryden, Suite 1500, Houston, TX 77030, USA.
J Plast Reconstr Aesthet Surg. 2009 Oct;62(10):e365-7. doi: 10.1016/j.bjps.2008.01.030. Epub 2008 Jul 18.
Digital metastases as the initial presenting sign of an occult pulmonary squamous cell carcinoma are very rare. While many tumours do progress to involve the digits in advanced stages, diagnosis of underlying lung cancer based on the initial presentation of a digital mass is very unusual. Clinically, metastasis to the phalanges typically results in notable tenderness, swelling, warmth and dull, throbbing pain. While nail avulsion with curettage and local tumour excision has been used in attempts to save the digit, amputation of the involved finger is by far the most frequent surgical methodology. Unfortunately, by this time, the primary tumour has invariably spread to diffusely involve other organs, and survival periods average only a few months. Management should be targeted to patient comfort, prevention of infection, and maintenance of function.
数字转移作为隐匿性肺鳞癌的初始表现非常罕见。虽然许多肿瘤在晚期会进展为累及手指,但基于数字肿块的初始表现诊断为肺癌是非常罕见的。临床上,指骨转移通常会导致明显的压痛、肿胀、发热和钝痛、悸动性疼痛。虽然已经使用指甲拔除术和局部肿瘤切除术来试图保留手指,但迄今为止,最常见的手术方法是截肢受累手指。不幸的是,此时,原发肿瘤已经扩散到广泛累及其他器官,平均生存时间仅为数月。治疗应针对患者的舒适度、预防感染和维持功能。