卵巢癌甲下转移：病例报告及文献简要回顾
Subungual Metastasis from Ovarian Cancer: Case Report and Brief Review of the Literature.
作者信息
Savoia Francesco, Medri Matelda, Raulli Gian Domenico, Menna Cecilia, Melandri Davide, Stanganelli Ignazio
机构信息
IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori," Skin Cancer Unit, Meldola, Italy.
Pathologic Anatomy, Ausl della Romagna, Santa Maria delle Croci Hospital, Ravenna, Italy.
出版信息
Skin Appendage Disord. 2023 Jan;9(1):54-57. doi: 10.1159/000526101. Epub 2022 Aug 29.
INTRODUCTION
Visceral solid cancers can metastasize in almost any organ, including the skin and its appendages.
CASE PRESENTATION
We report here the case of a 19-year-old Caucasian girl carrying a diagnosis of malignant germ cell tumor of the ovary, with pulmonary and brain metastases, that developed a painful red-violaceous subungual papule of the 4th finger of the left hand, associated with an over-curvature of the nail plate. Dermoscopy was characterized initially by different shades of pink and red, while after few weeks, it showed black pigmentation due to subcorneal hematomas, hemorrhagic crusts, and a rainbow pattern. Histology confirmed a diagnosis of a metastasis from a poorly differentiated carcinoma of ovarian origin.
DISCUSSION AND CONCLUSION
A brief review on the diagnosis and treatment of subungual metastases is reported.
引言
内脏实体癌几乎可转移至任何器官，包括皮肤及其附属器。
病例报告
我们在此报告一名19岁白种女孩的病例，她被诊断为卵巢恶性生殖细胞瘤，伴有肺和脑转移，左手无名指出现一个疼痛的紫红色甲下丘疹，并伴有甲板过度弯曲。皮肤镜检查最初表现为不同深浅的粉红色和红色，几周后，由于角膜下血肿、出血性结痂和彩虹图案，出现黑色色素沉着。组织学证实为卵巢来源的低分化癌转移。
讨论与结论
报告了关于甲下转移瘤诊断和治疗的简要综述。
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