Cushner F D, Friedman R J
Department of Orthopaedic Surgery, Medical University of South Carolina, Charleston.
Clin Orthop Relat Res. 1991 Aug(269):98-101.
Over a two-year period, 112 consecutive primary total knee arthroplasties (TKA) were performed according to a standard protocol and were evaluated to determine the effects of intraoperative tourniquet deflation, suction drainage, and immediate continuous passive motion (CPM) on blood loss and the need for blood transfusions. It has been reported that these measures lead to increased morbidity following TKA. The tourniquet was deflated before closure, hemostasis was obtained, and two suction drains were placed for 24 to 48 hours. CPM was started immediately, and continued for a mean of seven days. Serial hematocrits (Hct) were obtained. Mean age of the 64 males and 48 females was 65 years. The diagnosis was osteoarthritis in 86% and rheumatoid arthritis in 14%. Seventy-three percent of the prostheses were cemented and 27% were uncemented. The mean tourniquet time was 104 minutes and the mean length of surgery was 140 minutes. Blood loss measured at surgery averaged 222 ml. Total calculated blood loss averaged 794 ml, but was higher for patients with a cemented versus uncemented prosthesis (p less than .05), and males versus females (p less than .005). It was not related to diagnosis, tourniquet time, or length of surgery. Of the 38% of patients requiring a transfusion (mean, 2.2 units), there was not a significantly greater drop in Hct (from 36.6 to 26.5; change, 10.1) when compared to patients not receiving a transfusion (from 43.1 to 32.5; change, 10.6). Therefore, the need for transfusion was related to preoperative Hct and not the intraoperative or postoperative blood loss.(ABSTRACT TRUNCATED AT 250 WORDS)
在两年期间,按照标准方案连续进行了112例初次全膝关节置换术(TKA),并对其进行评估,以确定术中松开止血带、负压引流和立即持续被动运动(CPM)对失血和输血需求的影响。据报道,这些措施会导致TKA术后发病率增加。在关闭切口前松开止血带,实现止血,并放置两根负压引流管24至48小时。CPM立即开始,平均持续七天。获取系列血细胞比容(Hct)。64名男性和48名女性的平均年龄为65岁。诊断为骨关节炎的占86%,类风湿关节炎的占14%。73%的假体采用骨水泥固定,27%未采用骨水泥固定。平均止血带时间为104分钟,平均手术时长为140分钟。手术时测量的失血量平均为222毫升。计算得出的总失血量平均为794毫升,但采用骨水泥固定假体的患者与未采用骨水泥固定假体的患者相比失血量更高(p<0.05),男性与女性相比失血量更高(p<0.005)。它与诊断、止血带时间或手术时长无关。在需要输血的38%的患者中(平均2.2单位),与未接受输血的患者相比(从43.1降至32.5;变化10.6),其Hct的下降幅度(从36.6降至26.5;变化10.1)并没有显著更大。因此,输血需求与术前Hct有关,而非术中或术后失血。(摘要截断于250字)