Twetman S, Mattiasson A, Bratthall D
Medical and Dental Health Center, Lanssjukhuset, Halmstad, Sweden.
Oral Microbiol Immunol. 1990 Jun;5(3):169-71. doi: 10.1111/j.1399-302x.1990.tb00417.x.
The aim of this study was to obtain information about the quantitative distribution of salivary mutans streptococci and the relation to dental caries in children with contrasting levels of natural water fluoride. A total of 698 schoolchildren aged 12 yr were selected from areas with high (1.2 ppm) or low (0.1 ppm) fluoride concentration in the drinking water. They were all examined for the presence and number of mutans streptococci in saliva by a specially prepared plastic strip, the "Strip mutans" method, cultivated in a selective broth. Data on the caries experience were obtained from the dental records and from bite-wing radiographs. Mutans streptococci were identified in 82% of all children with no difference between the two areas. The number of mutans streptococci was however significantly (p less than 0.05) lower among the children from the high fluoride area than those from the low fluoride area. Children with no detectable or low levels (0-10 CFU) of mutans streptococci had less caries experience than children with moderate or high levels (11- greater than 500 CFU) in both areas investigated.
本研究的目的是获取有关天然水氟含量不同的儿童唾液变形链球菌定量分布及其与龋齿关系的信息。从饮用水中氟含量高（1.2 ppm）或低（0.1 ppm）的地区选取了698名12岁的学童。通过一种特制的塑料条“变形链球菌检测条”法，在选择性肉汤中培养，对他们唾液中变形链球菌的存在情况和数量进行了检测。龋齿经历的数据来自牙科记录和咬合翼片X光片。在所有儿童中，82%检测出变形链球菌，两个地区之间无差异。然而，高氟地区儿童的变形链球菌数量显著低于低氟地区儿童（p<0.05）。在两个调查地区，未检测到变形链球菌或变形链球菌水平低（0 - 10 CFU）的儿童比变形链球菌水平中等或高（11 - >500 CFU）的儿童龋齿经历更少。
