Cortimiglia R, Crescimanno G, Salerno M T, Amato G
Institute of Human Physiology, University of Palermo, Italy.
Exp Brain Res. 1991;84(3):471-7. doi: 10.1007/BF00230958.
The effect of claustrum (CL) stimulation on the spontaneous unitary activity of ipsi and contralateral frontal oculomotor neurons, was studied in chloralose-anaesthetized cats. A total of 205 units was bilaterally recorded in the medial oculomotor area, homologous of the primate "frontal eye fields"; 127 neurons were identified as projecting to the superior colliculus; for 33 of these last units stimulation of the ipsilateral CL provoked an excitatory effect lasting 10-25 ms and appearing with a latency of 5-15 ms; on 8 units the excitatory effect was followed by an inhibition lasting 100-250 ms. Ninety-eight of the 127 neurons were also tested through activation of the contralateral CL: 13 cells showed an excitatory effect lasting 10-35 ms and appearing with a latency of 20-50 ms. In three of the thirteen units the excitatory effect was followed by an inhibition lasting 100-150 ms. Complete section of the corpus callosum abolished the contralateral CL effect, suggesting the existence of a direct claustro-contralateral oculomotor cortex pathway running through the corpus callosum. The results could support the hypothesis that the CL may play a role in the bilateral control of the visuomotor performance.
在水合氯醛麻醉的猫中，研究了屏状核（CL）刺激对同侧和对侧额叶动眼神经元自发单位活动的影响。在内侧动眼神经区域共双侧记录了205个单位，该区域与灵长类动物的“额叶眼区”同源；127个神经元被确定为投射至上丘；对于其中33个最后的单位，刺激同侧CL会引发持续10 - 25毫秒、潜伏期为5 - 15毫秒的兴奋效应；在8个单位上，兴奋效应之后是持续100 - 250毫秒的抑制。127个神经元中的98个也通过激活对侧CL进行了测试：13个细胞表现出持续10 - 35毫秒、潜伏期为20 - 50毫秒的兴奋效应。在这13个单位中的3个，兴奋效应之后是持续100 - 150毫秒的抑制。胼胝体完全切断消除了对侧CL效应，表明存在一条通过胼胝体的直接屏状核 - 对侧动眼神经皮层通路。这些结果可能支持屏状核可能在视觉运动表现的双侧控制中起作用这一假说。
