Odijk Theo
Complex Fluids Theory, Faculty of Applied Sciences, Delft University of Technology, 2628 BC Delft, The Netherlands.
Phys Rev E Stat Nonlin Soft Matter Phys. 2008 Jun;77(6 Pt 1):060901. doi: 10.1103/PhysRevE.77.060901. Epub 2008 Jun 9.
A scaling analysis is presented of the statistics of long DNA confined in nanochannels and nanoslits. It is argued that there are several regimes in between the de Gennes and Odijk limits introduced long ago. The DNA chain folds back on itself giving rise to a global persistence length that may be very large owing to entropic deflection. Moreover, there is an orientational excluded-volume effect between the DNA segments imposed solely by the nanoconfinement. These two effects cause the chain statistics to be intricate leading to nontrivial power laws for the chain extension in the intermediate regimes. It is stressed that DNA confinement within nanochannels differs from that in nanoslits because the respective orientational excluded-volume effects are not the same.
本文对限制在纳米通道和纳米狭缝中的长链DNA统计特性进行了标度分析。研究表明，在很久以前引入的德热纳极限和奥迪克极限之间存在几种状态。DNA链自身折叠，由于熵致偏转产生了一个可能非常大的全局持久长度。此外，纳米限制仅对DNA片段施加了一个取向排除体积效应。这两种效应导致链统计特性变得复杂，从而在中间状态下链的延伸呈现出非平凡的幂律。需要强调的是，纳米通道内的DNA限制与纳米狭缝中的不同，因为各自的取向排除体积效应并不相同。
