Jones N R, Blumbergs P C, Brown C J, McLean A J, Manavis J, Perrett L V, Sandhu A, Scott G, Simpson D A
Department of Neurosurgery, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
J Clin Neurosci. 1998 Jan;5(1):73-9. doi: 10.1016/s0967-5868(98)90207-7.
Postmortem magnetic resonance (MR) scans were performed on the brains of 12 victims of fatal head injuries. These were compared with neuropathological studies of the entire brain. The first six subjects were imaged with the brain in situ and comparison was also made with antemortem computed tomography (CT). The brains from the subsequent six subjects were removed at autopsy, fixed in formalin and then imaged in a mitre box designed to overcome the problems encountered in the pilot study. Although both CT and MR imaging (MRI) detected all clinically relevant haemorrhagic lesions, many pathologically significant lesions were missed. MRI detected many more lesions than CT, but still failed to visualize areas of non-haemorrhagic axonal injury.
对12名致命头部损伤受害者的大脑进行了死后磁共振（MR）扫描。将这些扫描结果与对整个大脑的神经病理学研究进行了比较。前六个受试者的大脑在原位进行成像，并与生前计算机断层扫描（CT）进行了比较。后六个受试者的大脑在尸检时取出，用福尔马林固定，然后在一个为克服初步研究中遇到的问题而设计的斜接盒中进行成像。尽管CT和磁共振成像（MRI）都检测到了所有临床上相关的出血性病变，但许多具有病理意义的病变却被遗漏了。MRI检测到的病变比CT多得多，但仍未能显示非出血性轴索损伤区域。
