Buchala Samarasena, Wilson Julie C
Departments of Mathematics and Chemistry, University of York, York YO10 5YW, England.
Acta Crystallogr D Biol Crystallogr. 2008 Aug;D64(Pt 8):823-33. doi: 10.1107/S0907444908014273. Epub 2008 Jul 17.
Identifying the conditions that will produce diffraction-quality crystals can require very many crystallization experiments. The use of robots has increased the number of experiments performed in most laboratories, while in structural genomics centres tens of thousands of experiments can be produced every day. Reliable automated evaluation of these experiments is becoming increasingly important. A more robust classification is achieved by combining different methods of feature extraction with the use of multiple classifiers.
确定能够产生衍射质量晶体的条件可能需要进行大量的结晶实验。机器人的使用增加了大多数实验室进行的实验数量,而在结构基因组学中心,每天可以进行数以万计的实验。对这些实验进行可靠的自动评估变得越来越重要。通过将不同的特征提取方法与使用多个分类器相结合,可以实现更可靠的分类。