Saar Bettina, Gschossmann Juergen M, Bonel Harald M, Kickuth Ralph, Vock Peter, Netzer Peter
Department of Diagnostic, Interventional and Pediatric Radiology, Inselspital, University of Bern, Bern, Switzerland.
Invest Radiol. 2008 Aug;43(8):580-6. doi: 10.1097/RLI.0b013e31817e9af1.
To assess magnetic resonance (MR)-colonography (MRC) for detection of colorectal lesions using two different T1w three-dimensional (3D)-gradient-recalled echo (GRE)-sequences and integrated parallel data acquisition (iPAT) at a 3.0 Tesla MR-unit.
In this prospective study, 34 symptomatic patients underwent dark lumen MRC at a 3.0 Tesla unit before conventional colonoscopy (CC). After colon distension with tap water, 2 high-resolution T1w 3D-GRE [3-dimensional fast low angle shot (3D-FLASH), iPAT factor 2 and 3D-volumetric interpolated breathhold examination (VIBE), iPAT 3] sequences were acquired without and after bolus injection of gadolinium. Prospective evaluation of MRC was performed. Image quality of the different sequences was assessed qualitatively and quantitatively. The findings of the same day CC served as standard of reference.
MRC identified all polyps >5 mm (16 of 16) in size and all carcinomas (4 of 4) correctly. Fifty percent of the small polyps </=5 mm (4 of 8) were visualized by MRC. Diagnostic quality was excellent in 94% (384 of 408 colonic segments) using the 3D-FLASH and in 92% (376 of 408) for the VIBE. The 3D-FLASH sequence showed a 3-fold increase in signal-to-noise ratio (8 +/- 3.3 standard deviation (SD) in lesions without contrast enhancement (CE); 24.3 +/- 7.8 SD after CE). For the 3D-VIBE sequence, signal-to-noise ratio doubled in the detected lesions (147 +/- 54 SD without and 292 +/- 168 SD after CE). Although image quality was ranked lower in the VIBE, the image quality score of both sequences showed no statistical significant difference (chi > 0.6).
MRC using 3D-GRE-sequences and iPAT is feasible at 3.0 T-systems. The high-resolution 3D-FLASH was slightly preferred over the 3D-VIBE because of better image quality, although both used sequences showed no statistical significant difference.
在3.0特斯拉磁共振设备上，使用两种不同的T1加权三维（3D）梯度回波（GRE）序列和集成并行数据采集（iPAT）评估磁共振结肠成像（MRC）对结直肠病变的检测能力。
在这项前瞻性研究中，34例有症状的患者在进行传统结肠镜检查（CC）前，于3.0特斯拉设备上接受了暗腔MRC检查。在用自来水扩张结肠后，在静脉注射钆对比剂前和后分别采集了2个高分辨率T1加权3D-GRE序列[三维快速低角度激发（3D-FLASH），iPAT因子为2；以及三维容积内插屏气检查（VIBE），iPAT为3]。对MRC进行前瞻性评估。对不同序列的图像质量进行定性和定量评估。同日CC检查结果作为参考标准。
MRC正确识别了所有直径>5毫米的息肉（16个中的16个）和所有癌灶（4个中的4个）。50%的直径≤5毫米的小息肉（8个中的4个）可通过MRC显示。使用3D-FLASH序列时，94%（408个结肠节段中的384个）的诊断质量优秀；使用VIBE序列时，92%（408个中的376个）的诊断质量优秀。3D-FLASH序列的信噪比提高了3倍（无对比增强（CE）时病变的信噪比为8±3.3标准差（SD）；CE后为24.3±7.8 SD）。对于3D-VIBE序列，检测到的病变信噪比提高了一倍（无CE时为147±54 SD，CE后为292±168 SD）。尽管VIBE序列的图像质量排名较低，但两个序列的图像质量评分无统计学显著差异（卡方>0.6）。
在3.0 T系统上，使用3D-GRE序列和iPAT的MRC是可行的。高分辨率3D-FLASH序列因图像质量更好而略优于3D-VIBE序列，尽管两个使用的序列无统计学显著差异。
