Ajaj Waleed, Lauenstein Thomas C, Pelster Gregor, Goehde Susanne C, Debatin Joerg F, Ruehm Stefan G
Department of Diagnostic and Interventional Radiology, University Hospital, Essen, Germany.
J Magn Reson Imaging. 2004 Feb;19(2):216-21. doi: 10.1002/jmri.10455.
To prove the feasibility of air-distended magnetic resonance colonography (MRC) and compare it with water-based distention.
In five volunteers, the colon was imaged twice: once after distending the colon with air and a second time after distending the colon with water. A total of 50 patients, who had been referred to colonoscopy for a suspected colorectal pathology were randomized into water-distention (N = 25) and air-distention (N = 25) groups. A contrast-enhanced T1-weighted three-dimensional volume interpolated breath-hold (VIBE) sequence was collected. Comparative analysis was based on qualitative ratings of image quality and bowel distention, as well as contrast-to-noise ratio (CNR) measurements for the colonic wall with respect to the colonic lumen. In addition, patient acceptance was evaluated.
Inflammatory changes and colorectal masses were correctly identified on MRC in eight patients each. One 4-mm polyp identified at colonoscopy was missed on water-distended MRC. There were no false positive findings. No significant differences were found between air- and water-distention regarding discomfort levels and image quality. The presence of air in the colonic lumen was not associated with susceptibility artifacts. CNR of the contrast-enhanced colonic wall, as well as bowel distention, were superior on air-distended three-dimensional data sets.
MRC can be performed using either water or air for colonic distention. Both techniques permit assessment of the colonic wall and identification of colorectal masses. While discomfort levels are similar for both agents, MRC with air provides higher CNR and better colonic distention.
证明空气扩张磁共振结肠成像（MRC）的可行性，并将其与水扩张法进行比较。
对5名志愿者的结肠进行了两次成像：一次是在结肠用空气扩张后，另一次是在结肠用水扩张后。共有50例因疑似结直肠病变而接受结肠镜检查的患者被随机分为水扩张组（N = 25）和空气扩张组（N = 25）。采集了对比增强T1加权三维容积内插屏气（VIBE）序列。比较分析基于图像质量和肠管扩张的定性评分，以及结肠壁相对于结肠腔的对比噪声比（CNR）测量。此外，还评估了患者的接受程度。
在MRC上分别正确识别出8例患者的炎症性改变和结直肠肿物。在水扩张的MRC上漏诊了1例结肠镜检查发现的4毫米息肉。没有假阳性结果。在不适程度和图像质量方面，空气扩张和水扩张之间没有发现显著差异。结肠腔内的空气存在与磁敏感伪影无关。在空气扩张的三维数据集中，对比增强结肠壁的CNR以及肠管扩张情况更好。
MRC可以使用水或空气进行结肠扩张。两种技术都可以评估结肠壁并识别结直肠肿物。虽然两种介质引起的不适程度相似，但空气扩张的MRC提供了更高的CNR和更好的结肠扩张效果。
