Shore R C, Kirkham J, Robinson C, Moxham B J, Berkovitz B K
Department of Oral Biology, University of Leeds, U.K.
J Biol Buccale. 1991 Mar;19(1):68-73.
A quantitative structural analysis of the synthetic and degradative organelles of fibroblasts of rat incisor and molar periodontal ligaments was conducted. The results showed that in these tissues which are reported to have significantly different rates of turnover of their functional matrix collagen the rate of synthetic activity was the same. However, there were differences in the pattern of degradation with the molar ligament having between 5 and 6 times more phagocytosed collagen than the incisor. It is suggested that post-synthesis processing may control collagen turnover rather than modulation of rates of synthesis.
对大鼠切牙和磨牙牙周膜成纤维细胞的合成和降解细胞器进行了定量结构分析。结果表明，在这些据报道其功能性基质胶原蛋白周转率有显著差异的组织中，合成活性速率是相同的。然而，降解模式存在差异，磨牙韧带吞噬的胶原蛋白比切牙多5到6倍。有人认为，合成后加工可能控制胶原蛋白的周转，而不是调节合成速率。
