Svoboda E L, Shiga A, Deporter D A
Anat Rec. 1981 Apr;199(4):473-80. doi: 10.1002/ar.1091990404.
The purpose of this study was to assess the importance of the phagocytic mechanism of collagen resorption in the normal turnover and remodelling of soft connective tissues. Collagen phagocytosis by fibroblasts in rat skin, attached gingiva, and periodontal ligament was quantitated using the methodology of electron microscopic stereology. Periodontal ligament contained five and 15 times as much phagocytosed collagen as attached gingiva and skin respectively. Also, for each tissue examined, a positive correlation was observed between the amount of collagen phagocytosed and the known rate of mature collagen turnover.
本研究的目的是评估胶原吸收的吞噬机制在正常的软结缔组织更新和重塑中的重要性。使用电子显微镜体视学方法对大鼠皮肤、附着龈和牙周韧带中的成纤维细胞的胶原吞噬作用进行了定量分析。牙周韧带中吞噬的胶原分别是附着龈和皮肤的5倍和15倍。此外，对于所检查的每个组织，观察到吞噬的胶原量与已知的成熟胶原更新率之间呈正相关。
