来自海洋海绵伪角海绵属物种的两种新溴酪氨酸衍生物

Two new bromotyrosine derivatives from the marine sponge Pseudoceratina sp.

作者信息

Ma Ke, Yang Yi, Deng Zhiwei, de Voogd Nicole J, Proksch Peter, Lin Wenhan

机构信息

State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100083, P. R. China.

出版信息

Chem Biodivers. 2008 Jul;5(7):1313-20. doi: 10.1002/cbdv.200890118.

DOI:10.1002/cbdv.200890118

PMID:18649318

Abstract

Two new bromotyrosine alkaloids, purealidins T and U (1 and 2, resp.), along with five known bromotyrosines 3-7, were isolated from marine sponge Pseudoceratina sp. Their structures were elucidated on the basis of extensive spectroscopic data (CD, IR, 1D- and 2D-NMR, and MS) analysis.

摘要

从海洋海绵 Pseudoceratina sp. 中分离出两种新的溴酪氨酸生物碱，分别为 purealidins T 和 U（分别为 1 和 2），以及五种已知的溴酪氨酸 3 - 7。基于广泛的光谱数据（圆二色谱、红外光谱、一维和二维核磁共振光谱以及质谱）分析阐明了它们的结构。