Xie Su, Ling Xiangli
Affiliated Hospital of Guiyang Medical University, Guiyang 550004, China.
J Tradit Chin Med. 2008 Jun;28(2):129-33. doi: 10.1016/s0254-6272(08)60031-x.
To observe the regulative effect of auricular acupuncture, moxibustion and Chinese herbs on immunologic function in the D-galactose-induced aging mouse and to probe the feasibility and possible mechanisms for delaying aging, so as to provide experimental basis for acupuncture, moxibustion and Chinese herbs for delaying aging.
Aging mouse model was established by subcutaneous injection of D-galactose, and treated by auricular acupuncture, auricular acupuncture plus moxibustion, and auricular acupuncture plus Chinese herbs respectively for 6 weeks and then serum interleukin-2 (IL-2) and IL-6 contents and splenic lymphocyte transformation rate were compared among the groups.
Compared with the young group, the serum IL-2 level and the splenic lymphocyte transformation rate significantly decreased and the IL-6 level significantly increased in the aging mouse. After treatment by auricular acupuncture, auricular acupuncture plus Chinese herbs, especially auricular acupuncture plus moxibustion, the serum IL-2 level and the splenic lymphocyte transformation rate significantly increased, and the IL-6 level significantly decreased as compared with the model group.
Combined application of auricular acupuncture, moxibustion and Chinese herbs can improve the decline or dysfunction of immunological function in the aging organism to a certain extent.
观察耳针、艾灸及中药对D-半乳糖致衰老小鼠免疫功能的调节作用，探讨其延缓衰老的可行性及可能机制，为针灸及中药延缓衰老提供实验依据。
采用皮下注射D-半乳糖建立衰老小鼠模型，分别给予耳针、耳针加艾灸、耳针加中药治疗6周，比较各组血清白细胞介素-2（IL-2）、IL-6含量及脾淋巴细胞转化率。
与青年组比较，衰老小鼠血清IL-2水平及脾淋巴细胞转化率显著降低，IL-6水平显著升高。耳针、耳针加中药尤其是耳针加艾灸治疗后，与模型组比较，血清IL-2水平及脾淋巴细胞转化率显著升高，IL-6水平显著降低。
耳针、艾灸及中药联合应用可在一定程度上改善衰老机体免疫功能的衰退或紊乱。
