Katotomichelakis Michael, Balatsouras Dimitrios G, Bassioukas Konstantinos, Kontogiannis Nikolaos, Simopoulos Konstantinos, Danielides Vassilios
Department of Otolaryngology, Tzanion General Hospital of Piraeus, Greece.
J Med Case Rep. 2008 Jul 24;2:243. doi: 10.1186/1752-1947-2-243.
Prurigo nodularis is an unusual disorder of unknown aetiology, which is notoriously resistant to therapy, and is characterized by extremely pruritic nodules with well-defined clinical symptoms and histopathological findings.
We report the case of a patient presenting with pruritic papules and nodules on his legs, arms and trunk over the past 4 years, recurring after episodes of acute tonsillitis. Although oral and topical corticosteroids, oral antibiotics and emollients were used in his therapy, only tonsillectomy finally proved the definitive treatment.
We discuss the aetiopathogenesis, diagnosis and treatment of prurigo nodularis associated with chronic tonsillitis, and we further review the literature on this rare condition.
结节性痒疹是一种病因不明的罕见疾病，治疗效果 notoriously 不佳，其特征为伴有明确临床症状和组织病理学表现的极度瘙痒性结节。
我们报告一例患者，在过去4年中其腿部、手臂和躯干出现瘙痒性丘疹和结节，在急性扁桃体炎发作后复发。尽管在治疗中使用了口服和外用皮质类固醇、口服抗生素和润肤剂，但最终只有扁桃体切除术被证明是决定性的治疗方法。
我们讨论了与慢性扁桃体炎相关的结节性痒疹的病因发病机制、诊断和治疗，并进一步回顾了关于这种罕见疾病的文献。
