Age-related chances of mitochondrial cytochrome C oxidase and F0F1-ATP synthase subunit contents in rat cerebral cortex.
作者信息
Nicoletti V G, Tendi E A, Lalicata C, Reale S, Villa R F, Ragusa N, Giuffrida-Stella A M
机构信息
Institute of Biochemistry, Faculty of Medicine, University of Catania, Viale A. Doria 6, I-95125 Catania, Italy.
出版信息
Arch Gerontol Geriatr. 1996;22 Suppl 1:509-13. doi: 10.1016/0167-4943(96)86991-3.
PMID:18653086
Abstract
The levels of subunits I, II/III, and IV of cytochrome c oxidase and of subunits alpha, beta and gamma of F(0)F(1)-ATP synthase in inner mitochondrial membrane proteins purified from cerebral cortex of rat at 2, 6, 12, 18, 24, 26 months of age were analyzed by Western blot. Age-related changes in the content of subunits, encoded either in mitochondrial or nuclear DNA, were observed.
摘要
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