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澳大利亚外科住院患者不良事件的预测因素。

Predictors of adverse events in surgical admissions in Australia.

作者信息

Kable Ashley, Gibberd Robert, Spigelman Allan

机构信息

Faculty of Health, University of Newcastle, Australia.

出版信息

Int J Qual Health Care. 2008 Dec;20(6):406-11. doi: 10.1093/intqhc/mzn032. Epub 2008 Jul 24.

Abstract

OBJECTIVE

The purpose of this study was to determine risk factors of adverse events in five surgical procedures.

DESIGN

Retrospective record review was used to determine adverse events and risk factors of 1,177 surgical admissions. Procedures included in this study were transurethral resection of prostate, hysterectomy, hip and knee arthroplasty, cholecystectomy and herniorrhaphy. Risk factors included comorbidity, lifestyle factors and medications. Stepwise multiple logistic regression was used to determine predictors of adverse events.

SETTING

Two teaching hospitals in regional New South Wales, Australia.

PARTICIPANTS

1,177 surgical admissions for five high volume procedures.

MAIN OUTCOME MEASURES

Identified predictors of adverse events in surgical admissions.

RESULTS

The adverse event rate was 23.1% for all procedures (range 17.5-33.7% for the five procedures). Two factors were strongly predictive of an adverse event in all surgical admissions: age >70 years [odds ratio (OR) 1.9, 95% confidence intervals (CI) 1.3-2.6] and duration of operation (P = 0.005). Other predictive factors were: contaminated surgical site (OR 2.1, 95% CI 1.2-3.7) and anaemia (OR 1.8, 95% CI 1.1-2.8). Predictive factors of individual procedures included: urine retention (transurethral resection of the prostate); extended duration of operation and asthma (hysterectomy); acute admissions and extended duration of operation (cholecystectomy); and warfarin type drugs, ethanol abuse, failed prostheses, GI ulcer/inflammation, rheumatoid arthritis, and ischaemic heart disease (hip and knee joint arthroplasty).

CONCLUSIONS

The results of this study suggest that five factors should be routinely monitored for patients undergoing these procedures: age >70 years, type of procedure, duration of operation >2 h, contaminated surgical site and anaemia.

摘要

目的

本研究旨在确定五种外科手术中不良事件的风险因素。

设计

采用回顾性病历审查来确定1177例外科住院患者的不良事件和风险因素。本研究纳入的手术包括经尿道前列腺切除术、子宫切除术、髋膝关节置换术、胆囊切除术和疝修补术。风险因素包括合并症、生活方式因素和药物。采用逐步多元逻辑回归来确定不良事件的预测因素。

地点

澳大利亚新南威尔士州地区的两家教学医院。

参与者

1177例接受五种高流量手术的外科住院患者。

主要观察指标

确定外科住院患者不良事件的预测因素。

结果

所有手术的不良事件发生率为23.1%(五种手术的发生率范围为17.5 - 33.7%)。有两个因素在所有外科住院患者中强烈预测不良事件:年龄>70岁[比值比(OR)1.9,95%置信区间(CI)1.3 - 2.6]和手术持续时间(P = 0.005)。其他预测因素包括:手术部位污染(OR 2.1,95% CI 1.2 - 3.7)和贫血(OR 1.8,95% CI 1.1 - 2.8)。个别手术的预测因素包括:尿潴留(经尿道前列腺切除术);手术时间延长和哮喘(子宫切除术);急性入院和手术时间延长(胆囊切除术);以及华法林类药物、乙醇滥用、假体失败、胃肠道溃疡/炎症、类风湿性关节炎和缺血性心脏病(髋膝关节置换术)。

结论

本研究结果表明,对于接受这些手术的患者,应常规监测五个因素:年龄>70岁、手术类型、手术持续时间>2小时、手术部位污染和贫血。

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