Sviridkina L P, Borovaia E P, Makhneva A V
Vopr Kurortol Fizioter Lech Fiz Kult. 2008 May-Jun(3):12-5.
It is established that patients with coronary heart disease (CHD), received hirudotherapy (HT) as a part of sanatorium-spa treatment (SST), in comparison with patients, received only traditional SST, have tendency to normalization of initially increased levels of general cholesterol (GC) and triglycerides (TG), and to decrease in concentration of low-density lipoproteins (LDL). In elderly patients HT does not have an influence on levels of GC, TG and LDL, but increases level of high-density lipoproteins (HDL). Extension of SST by HT including maintains positive influence on indices of vegetative balance in CHD patients via mild activation of parasympathetic effects. In elderly patients additional prescription of HT sharply amplifies parasympathetic influences against the background of significant depression of sympathetic activity, which in patients with initial sympathicotonia leads to excessive parasympathetic shift of vegetative balance and can result in collapse of vascular tonus and aggravation of ischemic changes in myocardium. Therefore it is necessary to refine indications and contraindications to HT in CHD elderly patients.
已证实,与仅接受传统疗养院-温泉治疗(SST)的患者相比,作为疗养院-温泉治疗一部分接受水蛭疗法(HT)的冠心病(CHD)患者,其最初升高的总胆固醇(GC)和甘油三酯(TG)水平有趋于正常化的趋势,低密度脂蛋白(LDL)浓度降低。在老年患者中,HT对GC、TG和LDL水平没有影响,但会提高高密度脂蛋白(HDL)水平。通过HT延长SST包括通过轻度激活副交感神经效应,对CHD患者的自主神经平衡指标保持积极影响。在老年患者中,额外使用HT会在交感神经活动显著抑制的背景下大幅增强副交感神经影响,这在初始交感神经张力亢进的患者中会导致自主神经平衡过度向副交感神经转移,并可能导致血管张力崩溃和心肌缺血变化加重。因此,有必要明确CHD老年患者HT的适应证和禁忌证。