Shankar K M Pratap, Rao S Dattatreya, Umar Shaik Nafeez, Gopalakrishnaiah V
Department of Salya, Santhigiri Ayurvedic College, Palakkad, Kerala, India.
Department of Śalya, S.V. Ayurvedic College, Tirupati, India.
Anc Sci Life. 2014 Apr-Jun;33(4):236-41. doi: 10.4103/0257-7941.147432.
Skin diseases are among the most common health problems worldwide and are associated with a considerable burden. Eczema is such a skin ailment which cause psychological, social and financial burden on the patient and their families. Management of eczema with antibiotics, antihistamines, steroids etc., are available but even after their use relapses, recurrences and other complications are very common.
The aim of this study was to assess the efficacy of leech application in the management of vicarcikā (Eczema) with standard clinical parameters viz. Eczema Area and Severity Index (EASI) score, SCORing of Atopic Dermatitis (SCORAD) Index and Dermatology Life Quality Index (DLQI).
An open labeled clinical trial study without control group was conducted with 27 patients having the classical symptoms of vicarcikā (Eczema), selected as per the inclusion and exclusion criteria from outpatient department and inpatient department sections of Shalya Department, S.V. Ayurvedic Hospital, Tirupati. Minimum four sittings of leech application were carried out with 7 days interval. Pre- and post-treatment evaluation of the patient was done with Eczema Area and Severity Index (EASI) score, SCORing of Atopic Dermatitis (SCORAD) Index and Dermatology Life Quality Index (DLQI).
Analysis of the data was done with Student's paired t-test.
The total EASI score showed considerable reduction up to 54.45% (P < 0.01) and the SCORAD Index significantly reduced by 55% (P < 0.01). The life quality of the patient calculated by DLQI improved significantly by 62.36% (P < 0.01).
Leech application gives significant relief for the symptoms of eczema. The life quality of the patient also improved significantly after leech therapy. No adverse reactions were reported during the entire course of study.
皮肤病是全球最常见的健康问题之一,会带来相当大的负担。湿疹就是这样一种皮肤病,会给患者及其家庭造成心理、社会和经济负担。使用抗生素、抗组胺药、类固醇等治疗湿疹的方法虽有,但即便使用后,复发、再次发作及其他并发症仍很常见。
本研究旨在通过湿疹面积和严重程度指数(EASI)评分、特应性皮炎评分(SCORAD)指数和皮肤病生活质量指数(DLQI)等标准临床参数,评估水蛭疗法在治疗湿疮(湿疹)中的疗效。
在蒂鲁伯蒂市S.V.阿育吠陀医院外科门诊和住院部,根据纳入和排除标准选取27例有湿疮(湿疹)典型症状的患者,进行一项无对照组的开放标签临床试验研究。每隔7天进行至少4次水蛭疗法。治疗前后通过湿疹面积和严重程度指数(EASI)评分、特应性皮炎评分(SCORAD)指数和皮肤病生活质量指数(DLQI)对患者进行评估。
采用配对t检验对数据进行分析。
EASI总分显著降低达54.45%(P < 0.01),SCORAD指数显著降低55%(P < 0.01)。通过DLQI计算得出的患者生活质量显著改善62.36%(P < 0.01)。
水蛭疗法能显著缓解湿疹症状。水蛭疗法后患者的生活质量也显著改善。在整个研究过程中未报告不良反应。