Amjad Ali Imran, Pal Inam
Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan.
J Pak Med Assoc. 2008 May;58(5):272-4.
Ovarian squamous cell carcinoma is a rare malignancy and the occurrence is attributable to malignant transformation of an existing ovarian dermoid cyst. The de novo occurrence of squamous cell carcinoma of the ovary, in the absence of an antecedent ovarian dermoid, is extremely rare. The case of a 31 year old Asian woman, evaluated for abdominal distension and discomfort is presented. Abdominal CT was suggestive of a malignant neoplastic process. Laparotomy confirmed a malignant tumour with involvement of the right adnexa and extension into the omentum and bowel. Surgical debulking, hysterectomy, bilateral salpingo-ophorectomy and total omentectomy and bowel resection was performed. Histopathology demonstrated squamous cell carcinoma arising from the right ovary with no co-existing ovarian dermoid. The postoperative period was significant for disease progression despite adjuvant chemotherapy.
卵巢鳞状细胞癌是一种罕见的恶性肿瘤，其发生归因于现有的卵巢皮样囊肿的恶性转化。在没有先前卵巢皮样囊肿的情况下，卵巢鳞状细胞癌的原发性发生极为罕见。本文介绍了一名31岁亚洲女性因腹胀和不适接受评估的病例。腹部CT提示存在恶性肿瘤过程。剖腹手术证实为恶性肿瘤，累及右侧附件，并延伸至大网膜和肠道。进行了肿瘤细胞减灭术、子宫切除术、双侧输卵管卵巢切除术、全大网膜切除术和肠切除术。组织病理学显示鳞状细胞癌起源于右侧卵巢，不存在并存的卵巢皮样囊肿。尽管进行了辅助化疗，但术后疾病仍有显著进展。
