Lavazec Catherine, Bourgouin Catherine
Institut Pasteur, Unité de génétique et génomique des insectes vecteurs, 28 rue du Docteur Roux, 75015 Paris, France.
Microbes Infect. 2008 Jul;10(8):845-9. doi: 10.1016/j.micinf.2008.05.004. Epub 2008 May 22.
Reduction of transmission is critical for effective malaria control. Transmission blocking vaccines, which are intended to prevent the parasites from infecting the mosquito vectors, could target mosquito antigens that are required for the successful development of the parasite in its vector. Here we review recent advances in the identification of promising candidate antigens for a mosquito-based transmission blocking vaccine.
减少传播对于有效控制疟疾至关重要。传播阻断疫苗旨在防止寄生虫感染蚊虫媒介，它可以针对寄生虫在其媒介中成功发育所需的蚊虫抗原。在此，我们综述了在鉴定有前景的基于蚊虫的传播阻断疫苗候选抗原方面的最新进展。
