Roswall Nina, Olsen Anja, Christensen Jane, Rugbjerg Kathrine, Mellemkjaer Lene
Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden 49, DK-2100 Copenhagen Ø, Denmark.
Eur J Cancer. 2008 Sep;44(14):2058-73. doi: 10.1016/j.ejca.2008.06.011. Epub 2008 Jul 25.
We investigated the effects of socioeconomic, demographic and health-related indicators on the incidence of and survival from haematological cancers diagnosed in 1994-2003 with follow-up through 2006 in Denmark using information from nationwide registers. The analyses were based on data on 636 patients with Hodgkin lymphoma (HL), 4516 with non-Hodgkin lymphoma (NHL) and 3486 with leukaemia in a cohort of 3.22 million people born between 1925 and 1973 and aged >or=30 years. No consistent differences in incidence were seen by socioeconomic position, but an association with comorbidity was found. Patients in the lowest socioeconomic groups and those with other serious illnesses, especially men, had a worse survival of NHL. Survival results for leukaemia tended to be similar to those for NHL, although associations were generally weaker and insignificant. Thus, there were no strong associations between socioeconomic position and the incidence of these cancers; survival after NHL might be affected.
我们利用丹麦全国性登记处的信息,调查了社会经济、人口统计学和健康相关指标对1994年至2003年诊断出的血液系统癌症发病率及生存率的影响,并对这些患者随访至2006年。分析基于一个由出生于1925年至1973年且年龄≥30岁的322万人组成的队列中的636例霍奇金淋巴瘤(HL)患者、4516例非霍奇金淋巴瘤(NHL)患者和3486例白血病患者的数据。社会经济地位方面未发现发病率存在一致差异,但发现与合并症有关联。社会经济地位最低的群体以及患有其他严重疾病的患者,尤其是男性,非霍奇金淋巴瘤的生存率较差。白血病的生存结果往往与非霍奇金淋巴瘤相似,尽管关联通常较弱且不显著。因此,社会经济地位与这些癌症的发病率之间没有强烈关联;非霍奇金淋巴瘤后的生存可能会受到影响。