Baastrup Rikke, Sørensen Mette, Hansen Johnni, Hansen Rikke Dalgaard, Würtzen Hanne, Winther Jeanette Falck
Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden 49, DK-2100 Copenhagen Ø, Denmark.
Eur J Cancer. 2008 Sep;44(14):1962-77. doi: 10.1016/j.ejca.2008.06.013. Epub 2008 Jul 25.
We investigated the effect of socioeconomic, demographic and health-related indicators on the incidence of and survival from cancers of the oesophagus, stomach and pancreas diagnosed during 1994-2003 with follow-up through 2006 in Denmark using information from nationwide registers. The analyses were based on data on 2075 patients with cancer of the oesophagus, 2673 with stomach cancer and 3657 with pancreatic cancer in a cohort of 3.22 million persons born between 1925 and 1973 and aged >or=30 years. Overall, we found decreasing incidence rates of all three gastrointestinal cancers with increasing social advantage; this was most pronounced for oesophageal cancer and least for pancreatic cancer. The effect of socioeconomic position on survival after these cancers was less clear, perhaps due to the poor relative survival from these cancers and the fact that all three cancers are relatively rare in Denmark.
我们利用全国登记处的信息,调查了社会经济、人口统计学和健康相关指标对1994年至2003年期间在丹麦诊断出的食管癌、胃癌和胰腺癌的发病率及生存率的影响,并对这些患者进行随访至2006年。分析基于在1925年至1973年出生且年龄≥30岁的322万人队列中的2075例食管癌患者、2673例胃癌患者和3657例胰腺癌患者的数据。总体而言,我们发现随着社会优势的增加,这三种胃肠道癌症的发病率均呈下降趋势;食管癌最为明显,胰腺癌最不明显。社会经济地位对这些癌症患者生存率的影响不太明确,这可能是由于这些癌症的相对生存率较低,以及这三种癌症在丹麦都相对罕见。