Ino A, Ogoshi T, Okunomiya Y
Mie Prefectural Psychiatric Hospital, Takachaya.
Seishin Shinkeigaku Zasshi. 1991;93(5):334-58.
595 alcohol dependent cases had been enrolled in the Mie Danshu-Shinsei-Kai (The Alcohol Abstinence Club in Mie) since its establishment in Jan. 1972 by Oct. 1984 when this study started. 163 cases of them, who had been practising abstinence at least for 6 months when the first observation was made in Oct. 1984, were selected for the follow-up study. Relapses in these cases were checked twice, 2.5 years later in 1987 and 5 years later in 1989. The results obtained were summarized as follows: It was observed that 64% of those who had practised abstinence for 2 years sustained abstinence successfully at least for the next 5 years, and 74% of those who had kept non-drinking for 3 years continued abstinence for the next 5 years. Those who had practised abstinence for shorter than 2 years just before the first observation showed that the closer the term of abstinence approached to 2 years, the more sharply the following 5 year abstinence rate increased. It was noticed among those who had kept abstinence for longer than 3 years that the longer the abstinence period became, the more slowly the next 5 year abstinence rate increased, eventually reaching to as high as 81%. A turning point from sharp increase to slow increase was found in between 2 and 3 years of abstinence. From the observation mentioned above, the period of abstinence can be classified into three categories in view of prognosis: shorter than 2 years, 2 to 3 years, and longer than 3 years, which stand for "unstable," "intermediate," and "stable" period respectively. The intermediate period is considered to be critically important in terms of prognosis and treatment of alcohol dependence. It would be reasonable therefore to prospect prognosis in the short term or in the long term basis according to the period of abstinence. The object and contents of treatment might become different before and after the intermediate period. The major factors which affect the prognosis can be classified into 5 categories; 1) the degree of insight into his or her drinking, 2) biological condition, 3) financial problems like "debt," 4) tendency toward multiple addiction, and 5) problems of "co-dependency." It was noticed that although all of these factors remained unresolved in most cases of unstable period, factors 1), 2) and 3) were mostly successfully resolved in a stable period. Factors 4) and 5) are found in not rarely even in a stable period.(ABSTRACT TRUNCATED AT 400 WORDS)
自1972年1月三重丹舒-新生会(三重戒酒俱乐部)成立至1984年10月本研究开始时,共有595例酒精依赖患者登记入会。其中,163例在1984年10月首次观察时已戒酒至少6个月,被选入随访研究。对这些患者的复饮情况进行了两次检查,分别在1987年(首次观察2.5年后)和1989年(首次观察5年后)。结果总结如下:观察发现,戒酒满2年的患者中,64%至少在接下来的5年里成功保持戒酒;戒酒满3年的患者中,74%在接下来的5年里继续保持戒酒。首次观察前戒酒时间短于2年的患者显示,戒酒时间越接近2年,接下来5年的戒酒率增长越显著。在戒酒超过3年的患者中发现,戒酒时间越长,接下来5年的戒酒率增长越缓慢,最终高达81%。在戒酒2至3年之间发现了从快速增长到缓慢增长的转折点。从上述观察来看,从预后角度,戒酒期可分为三类:短于2年、2至3年、长于3年,分别代表“不稳定”“中间”和“稳定”期。中间期在酒精依赖的预后和治疗方面被认为至关重要。因此,根据戒酒期进行短期或长期预后预测是合理的。中间期前后治疗的目标和内容可能会有所不同。影响预后的主要因素可分为5类:1)对饮酒的自知力程度;2)生物学状况;3)如“债务”等经济问题;4)多重成瘾倾向;5)“共依存”问题。注意到,虽然在不稳定期的大多数病例中所有这些因素都未得到解决,但在稳定期,因素1)、2)和3)大多成功得到解决。即使在稳定期,因素4)和5)也并不罕见。(摘要截选至400字)