Gut. 1971 Aug;12(8):616-8. doi: 10.1136/gut.12.8.616.
Human basal gastric secretion is markedly reduced after oral administration of 10 mg diazepam. This effect lasts for five hours.Gastric nocturnal secretion, collected five hours after the last meal, reveals a decline towards the morning hours with an average of 25% in placebo-treated patients. A comparison between placebo and diazepam reveals a significantly greater decrease of 47% in volume after giving parenterally 10 mg diazepam without noticeable side effects.
口服 10 毫克地西泮后,人体基础胃酸分泌明显减少。这种作用持续 5 小时。收集最后一次餐后 5 小时的夜间胃液发现,胃分泌量呈下降趋势,直至清晨,安慰剂治疗患者平均下降 25%。将 10 毫克地西泮静脉给予安慰剂和地西泮组患者后进行比较,发现地西泮组的胃液量明显减少 47%,而无明显副作用。