Guo B, Wang Y, Sun X, Tang K
Shanghai Key Laboratory of Agrobiotechnology, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200030, PR China.
Prikl Biokhim Mikrobiol. 2008 Mar-Apr;44(2):153-8.
Endophytes, microorganisms that reside in the internal tissues of living plants without causing any immediate overt negative effects, have been found in every plant species examined to date and recognized as potential sources of novel natural products for exploitation in medicine, agriculture, and industry with more and more bioactive natural products isolated from the microorganisms. In this review, we focus mainly on bioactive natural products from endophytic microorganisms by their different functional roles. The prospect and facing problems of isolating natural products from endophytes are also discussed.
内生菌是指存在于活植物内部组织中且不会立即造成任何明显负面影响的微生物。迄今为止，在每一种被检测的植物物种中都发现了内生菌，并且随着越来越多具有生物活性的天然产物从这些微生物中被分离出来，内生菌被认为是医药、农业和工业领域新型天然产物开发的潜在来源。在本综述中，我们主要根据内生微生物不同的功能作用，聚焦于其产生的生物活性天然产物。同时也讨论了从内生菌中分离天然产物的前景及面临的问题。
