Poliak R Ia, Voĭtsekhovskiĭ B L, Dubrovina T Ia, Dukhin A I, Ivanova I A, Koltyreva T V, Kramskaia T A, Leont'eva G F, Meringova L F, Chetverikova L K
Vestn Akad Med Nauk SSSR. 1991(4):34-40.
The authors made a comparative analysis of the contribution to the outcome of the disease by realization of information of viral genome and host responses in the time-course of simulated lethal and nonlethal mice influenza. They studied the effect of ionol, pathogenetic antioxidant, prevention and depicted absolutely new features of the diseases severity and outlined possible points of effective drug application. The suggested scheme of the time-course measurement of viral involvement of the host body and the formation of its responses could be recommended in the study of mechanisms of the viral infection development and the activity of antiviral agents.
作者对在模拟致死性和非致死性小鼠流感病程中，病毒基因组信息的实现和宿主反应对疾病结局的贡献进行了比较分析。他们研究了致病抗氧化剂离子醇的预防作用，并描述了疾病严重程度的全新特征，概述了有效药物应用的可能切入点。所建议的宿主机体病毒感染过程及反应形成的时间进程测量方案，可推荐用于病毒感染发展机制及抗病毒药物活性的研究。
