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孕妇脊柱疾病的临床处理及手术策略:10例报告

Clinical approach and surgical strategy for spinal diseases in pregnant women: a report of ten cases.

作者信息

Han In-Ho, Kuh Sung-Uk, Kim Jae-Hoon, Chin Dong-Kyu, Kim Keun-Su, Yoon Young-Sul, Jin Byung-Ho, Cho Yong-Eun

机构信息

Department of Neurosurgery, Spine and Spinal Cord Institute, Yongdong Severance Spine Hospital, Yonsei University College of Medicine, Seoul, Korea.

出版信息

Spine (Phila Pa 1976). 2008 Aug 1;33(17):E614-9. doi: 10.1097/BRS.0b013e31817c6c7d.

Abstract

STUDY DESIGN

Case series retrospective review.

OBJECTIVE

To present the treatment guideline for spinal diseases in pregnant women.

SUMMARY OF BACKGROUND DATA

Treatment for spinal diseases in pregnant women is a special clinical challenge because of complex medical and surgical clinical problems.

METHODS

We retrospectively reviewed 10 patients who underwent surgery for spinal diseases, who were diagnosed during pregnancy at our hospital from February 1992 to October 2005. Six patients had herniated lumbar discs, 3 patients had spinal tumors, and 1 patient had spinal tuberculosis.

RESULTS

Five patients with HLDs underwent partial hemilaminectomy and discectomy during pregnancy and maintained the pregnancy. One patient underwent posterior lumbar interbody fusion and had a therapeutic abortion 6 days after lumbar surgery. In 1 patient with hemangioblastoma at the level of T8-T9 level, prepartum surgery was performed maintaining pregnancy in gestational age, 29 weeks. In another patient with hemangioblastoma at the T10 level, a preoperative cesarean section and tumor removal surgery were performed under the same anesthesia in gestational age 34 weeks. One patient had recurrent intramedullary ependymoma at the C3-T2 level. She had the preterm baby by vaginal delivery before spinal operation in gestational age 33 weeks and underwent tumor removal surgery. One patient with tuberculous spondylitis at the level of T3-T5 level, therapeutic abortion performed in gestational age, 16 weeks because of inevitable radiation exposure during fusion surgery.

CONCLUSION

In most spinal diseases, including HLD and tumors, prepartum surgical treatment can be safely performed maintaining pregnancy. For patients with progressive neurologic deficit at 34 to 36 weeks gestation or later, spine surgery should be performed following the induction of delivery or a cesarean section, or at the same time.

摘要

研究设计

病例系列回顾性研究。

目的

提出孕妇脊柱疾病的治疗指南。

背景资料总结

由于存在复杂的内科和外科临床问题,孕妇脊柱疾病的治疗是一项特殊的临床挑战。

方法

我们回顾性分析了1992年2月至2005年10月在我院孕期诊断为脊柱疾病并接受手术的10例患者。6例为腰椎间盘突出症,3例为脊柱肿瘤,1例为脊柱结核。

结果

5例腰椎间盘突出症患者在孕期接受了部分半椎板切除术和椎间盘切除术,并维持了妊娠。1例患者接受了后路腰椎椎间融合术,术后6天进行了治疗性流产。1例T8 - T9水平的血管母细胞瘤患者,在孕29周时进行了产前手术并维持妊娠。另1例T10水平血管母细胞瘤患者,在孕34周时在同一麻醉下进行了剖宫产和肿瘤切除术。1例C3 - T2水平复发性髓内室管膜瘤患者,在孕33周时脊柱手术前经阴道分娩早产,随后进行了肿瘤切除术。1例T3 - T5水平结核性脊柱炎患者,因融合手术中不可避免的辐射暴露,在孕16周时进行了治疗性流产。

结论

在大多数脊柱疾病中,包括腰椎间盘突出症和肿瘤,产前手术治疗可安全进行并维持妊娠。对于妊娠34至36周及以后出现进行性神经功能缺损的患者,应在引产或剖宫产术后或同时进行脊柱手术。

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