Judson Richard, Richard Ann, Dix David, Houck Keith, Elloumi Fathi, Martin Matthew, Cathey Tommy, Transue Thomas R, Spencer Richard, Wolf Maritja
National Center for Computational Toxicology, U.S. Environmental Protection Agency, 109 T.W. Alexander Drive, Research Triangle Park, NC 27711, USA.
Toxicol Appl Pharmacol. 2008 Nov 15;233(1):7-13. doi: 10.1016/j.taap.2007.12.037. Epub 2008 Jul 11.
ACToR (Aggregated Computational Toxicology Resource) is a database and set of software applications that bring into one central location many types and sources of data on environmental chemicals. Currently, the ACToR chemical database contains information on chemical structure, in vitro bioassays and in vivo toxicology assays derived from more than 150 sources including the U.S. Environmental Protection Agency (EPA), Centers for Disease Control (CDC), U.S. Food and Drug Administration (FDA), National Institutes of Health (NIH), state agencies, corresponding government agencies in Canada, Europe and Japan, universities, the World Health Organization (WHO) and non-governmental organizations (NGOs). At the EPA National Center for Computational Toxicology, ACToR helps manage large data sets being used in a high-throughput environmental chemical screening and prioritization program called ToxCast.
ACToR(综合计算毒理学资源库)是一个数据库以及一套软件应用程序,它将有关环境化学品的多种类型和来源的数据整合到一个中心位置。目前,ACToR化学数据库包含来自150多个来源的化学结构、体外生物测定和体内毒理学测定信息,这些来源包括美国环境保护局(EPA)、疾病控制中心(CDC)、美国食品药品监督管理局(FDA)、国立卫生研究院(NIH)、各州机构、加拿大、欧洲和日本的相应政府机构、大学、世界卫生组织(WHO)以及非政府组织(NGO)。在美国环境保护局国家计算毒理学中心,ACToR有助于管理一个名为ToxCast的高通量环境化学品筛选和优先级排序计划中所使用的大型数据集。