Volle R L, Branisteanu D D
Naunyn Schmiedebergs Arch Pharmacol. 1976 Nov;295(2):103-8. doi: 10.1007/BF00499440.
Estimates of quantal release parameters at frog neuromuscular junctions showed that alterations in [Ca2+]o affected m (number of quanta), p (probability of quantal release) and n (stores of quanta available for release). The effect of [Ca2+]o depended upon the initial value for p. When p was low, raising [Ca2+]o increased m and p, but not n. However, when p was large, raising [Ca2+]o had no further effect on p but increased m and n. During prolonged repetitive nerve stimulation to cause a decrease in m, n was decreased and p was increased. This finding was attributed to a failure of transmitter mobilization to maintain the stores of transmitter available for release.
对青蛙神经肌肉接头处量子释放参数的估计表明，细胞外钙离子浓度（[Ca2+]o）的改变会影响m（量子数量）、p（量子释放概率）和n（可供释放的量子储备）。[Ca2+]o的影响取决于p的初始值。当p较低时，提高[Ca2+]o会增加m和p，但不会增加n。然而，当p较大时，提高[Ca2+]o对p没有进一步影响，但会增加m和n。在长时间重复神经刺激导致m降低的过程中，n降低而p升高。这一发现归因于递质动员失败，无法维持可供释放的递质储备。
