Goodman Suzan, Hendlish Sarah K, Reeves Matthew F, Foster-Rosales Anne
University of California, San Francisco, San Francisco, CA 94110, USA.
Contraception. 2008 Aug;78(2):143-8. doi: 10.1016/j.contraception.2008.03.003. Epub 2008 May 14.
Of the 1.3 million abortions performed annually in the United States, approximately half are repeat procedures. Immediate postabortal intrauterine device (IUD) insertion is a safe, effective, practical and underutilized intervention that we hypothesize will significantly decrease repeat unintended pregnancy and abortion.
All women receiving immediate postabortal IUD insertion in eight clinics of a Northern California Planned Parenthood agency during a 3-year period comprise the IUD cohort. We selected a cohort of controls receiving abortions but choosing other, non-IUD contraception on the day of the abortion visit in a 2:1 ratio matched by date of abortion. We obtained follow-up data on repeat abortions within the agency for both cohorts through 14 months after the 3-year period. We evaluated differences in repeat abortion between cohorts. All analyses were intent-to-treat.
Women who received an immediate postabortal IUD had a lower rate of repeat abortions than controls (p<.001). Women who received a postabortal IUD had 34.6 abortions per 1000 woman-years of follow-up compared to 91.3 for the control group. The hazard ratio for repeat abortion was 0.38 [95% confidence interval (CI), 0.27-0.53] for women receiving a postabortal IUD compared to controls. When adjusted for age, race/ethnicity, marital status, and family size, the hazard ratio was 0.37 (95% CI, 0.26-0.52).
Immediate postabortal intrauterine contraception has the potential to significantly reduce repeat abortion.
在美国,每年进行的130万例堕胎手术中,约有一半是重复手术。流产后立即插入宫内节育器(IUD)是一种安全、有效、实用但未得到充分利用的干预措施,我们推测这将显著减少重复意外怀孕和堕胎的情况。
在三年期间,北加利福尼亚计划生育机构的八家诊所中所有接受流产后立即插入IUD的女性组成IUD队列。我们以2:1的比例选择了一组在堕胎当天接受堕胎但选择其他非IUD避孕方法的对照组,根据堕胎日期进行匹配。我们通过三年期后的14个月获得了两个队列在该机构内重复堕胎的随访数据。我们评估了队列之间重复堕胎的差异。所有分析均采用意向性治疗。
接受流产后立即插入IUD的女性重复堕胎率低于对照组(p<.001)。接受流产后IUD的女性每1000妇女年随访中有34.6例堕胎,而对照组为91.3例。与对照组相比,接受流产后IUD的女性重复堕胎的风险比为0.38 [95%置信区间(CI),0.27 - 0.53]。在对年龄、种族/族裔、婚姻状况和家庭规模进行调整后,风险比为0.37(95%CI,0.26 - 0.52)。
流产后立即进行宫内避孕有可能显著减少重复堕胎。