Romano Jose G, Schulz Patricia, Kenkel Sigrid, Todd David P
University of Miami, Miller School of Medicine, Miami, Florida 33136, United States.
J Neurol Sci. 2008 Oct 15;273(1-2):70-4. doi: 10.1016/j.jns.2008.06.026. Epub 2008 Jul 30.
The objective of this study was to determine the effect of a visual rehabilitation intervention on visual field defects in a US cohort. Vision Restoration Therapy (VRT) consists of a specific pattern of stimulation that is directed at the border of the blind field.
This retrospective study evaluated individuals with homonymous visual field defect from retrochiasmatic lesions treated with 6 modules of VRT. Suprathreshold visual field testing of the central 43x32 was obtained at baseline and after each module. The main outcome measures were the change in stimuli detection and the shift in the position of the border of the blind field. The impact of age, time from injury and type of visual field defect were analyzed.
Among 161 patients, the mean absolute improvement in stimuli detection was 12.8%. The average border shift was 4.87. Improvements of > or =3% was noted in 76% of patients. Absolute change in stimulus detection of > or =3% at mid-therapy was associated with a greater final improvement. Age, time from lesion and type of visual field defect did not influence the degree of field expansion.
VRT improves stimulus detection and results in a shift of the position of the border of the blind field as measured on suprathreshold visual field testing. These results support prior reports and support VRT as a useful rehabilitative intervention for a proportion of patients with visual field defects from retrochiasmatic lesions.
本研究的目的是确定视觉康复干预对美国一组队列中视野缺损的影响。视觉恢复疗法(VRT)由针对盲视野边界的特定刺激模式组成。
这项回顾性研究评估了接受6个模块VRT治疗的视交叉后病变导致的同向性视野缺损患者。在基线时以及每个模块治疗后,对中央43x32区域进行超阈值视野测试。主要结局指标是刺激检测的变化以及盲视野边界位置的移动。分析了年龄、受伤时间和视野缺损类型的影响。
在161例患者中,刺激检测的平均绝对改善率为12.8%。平均边界移动为4.87。76%的患者改善幅度≥3%。治疗中期刺激检测的绝对变化≥3%与最终更大的改善相关。年龄、病变时间和视野缺损类型不影响视野扩展程度。
VRT可改善刺激检测,并导致超阈值视野测试中盲视野边界位置的移动。这些结果支持先前的报告,并支持VRT作为对视交叉后病变所致视野缺损部分患者有用的康复干预措施。