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功能化杯[n]芳烃作为生物化合物的膜转运体。一篇综述。

Functionalized calix[n]arenes as membrane transporters for biological compounds. A minireview.

作者信息

Mutihac Lucia

机构信息

University of Bucharest, Department of Analytical Chemistry, 4-12 Blvd., Regina Elisabeta, Bucharest, Romania.

出版信息

Curr Drug Discov Technol. 2008 Jun;5(2):98-104. doi: 10.2174/157016308784746256.

Abstract

The present minireview summarizes some potential applications of calix[n]arenes family in binding and transport through liquid membranes of various biological compounds. In this respect, some specific aspects of their applications as carriers through liquid membrane are discussed in view of their potential for development of new drug formulation. The place of calix[n]arenes in the interesting and challenging field of transmembrane ion transport as synthetic ionophores is briefly outlined.

摘要

本综述总结了杯[n]芳烃家族在结合和通过液膜转运各种生物化合物方面的一些潜在应用。在这方面,鉴于它们在开发新药物制剂方面的潜力,讨论了它们作为液膜载体应用的一些具体方面。简要概述了杯[n]芳烃作为合成离子载体在跨膜离子转运这一有趣且具有挑战性的领域中的地位。

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