The agouti mouse model: an epigenetic biosensor for nutritional and environmental alterations on the fetal epigenome.
作者信息
Dolinoy Dana C
机构信息
Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina 27710, USA.
出版信息
Nutr Rev. 2008 Aug;66 Suppl 1(Suppl 1):S7-11. doi: 10.1111/j.1753-4887.2008.00056.x.
Abstract
摘要
相似文献
1
The agouti mouse model: an epigenetic biosensor for nutritional and environmental alterations on the fetal epigenome.刺豚鼠小鼠模型：一种用于检测营养和环境变化对胎儿表观基因组影响的表观遗传生物传感器。
Nutr Rev. 2008 Aug;66 Suppl 1(Suppl 1):S7-11. doi: 10.1111/j.1753-4887.2008.00056.x.
2
The Agouti mouse: a biosensor for environmental epigenomics studies investigating the developmental origins of health and disease.刺豚鼠：一种用于环境表观基因组学研究的生物传感器，用于探究健康与疾病的发育起源。
Epigenomics. 2014;6(5):447-50. doi: 10.2217/epi.14.58.
3
Environmental influence on epigenetic inheritance at the Avy allele.环境对Avy等位基因表观遗传的影响。
Nutr Rev. 2008 Aug;66 Suppl 1:S12-4. doi: 10.1111/j.1753-4887.2008.00057.x.
4
Diet-induced hypermethylation at agouti viable yellow is not inherited transgenerationally through the female.饮食诱导的刺豚鼠可变黄色基因位点的高甲基化不会通过雌性进行跨代遗传。
FASEB J. 2007 Oct;21(12):3380-5. doi: 10.1096/fj.07-8229com. Epub 2007 Jun 5.
5
Adaptive radiation-induced epigenetic alterations mitigated by antioxidants.抗氧化剂减轻适应性辐射诱导的表观遗传改变。
FASEB J. 2013 Feb;27(2):665-71. doi: 10.1096/fj.12-220350. Epub 2012 Nov 1.
6
Sequencing of part of the goat agouti gene and SNP identification.
Biochem Genet. 2010 Feb;48(1-2):152-6. doi: 10.1007/s10528-009-9307-6. Epub 2009 Nov 22.
7
Epigenetic inheritance at the agouti locus in the mouse.小鼠刺鼠基因座的表观遗传继承
Nat Genet. 1999 Nov;23(3):314-8. doi: 10.1038/15490.
8
ASIP gene variation in Chinese donkeys.中国驴的ASIP基因变异
Anim Genet. 2017 Jun;48(3):372-373. doi: 10.1111/age.12530. Epub 2017 Feb 15.
9
Agouti germ line gets acquisitive.
Nat Genet. 1999 Nov;23(3):254-6. doi: 10.1038/15425.
10
A 4-bp deletion in the ASIP gene is associated with the recessive black coat colour in domestic guinea pigs (Cavia porcellus).ASIP基因中的一个4碱基对缺失与家养豚鼠（豚鼠）的隐性黑色皮毛颜色有关。
Anim Genet. 2019 Apr;50(2):190-191. doi: 10.1111/age.12766. Epub 2019 Feb 12.
引用本文的文献
1
Molecular Mechanisms Against Successful Weight Loss and Promising Treatment Options in Obesity.肥胖症中阻碍成功减重的分子机制及前景广阔的治疗选择
Biomedicines. 2025 Aug 15;13(8):1989. doi: 10.3390/biomedicines13081989.
2
Potential Epigenetic Impacts of Phytochemicals on Ruminant Health and Production: Connecting Lines of Evidence.植物化学物质对反刍动物健康和生产的潜在表观遗传影响：连接证据链
Animals (Basel). 2025 Jun 17;15(12):1787. doi: 10.3390/ani15121787.
3
Ultra-rapid lispro or fast-acting aspart compared to standard insulin lispro and aspart using closed-loop insulin therapy: a systematic review and meta-analysis of randomized control trials.与标准赖脯胰岛素和门冬胰岛素相比，超快速赖脯胰岛素或速效门冬胰岛素用于闭环胰岛素治疗：随机对照试验的系统评价和荟萃分析
Front Endocrinol (Lausanne). 2025 Jun 6;16:1600157. doi: 10.3389/fendo.2025.1600157. eCollection 2025.
4
Rapid Neural DNA Methylation Responses to Predation Stress in Trinidadian Guppies.特立尼达孔雀鱼对捕食压力的快速神经DNA甲基化反应
Mol Ecol. 2025 May;34(10):e17774. doi: 10.1111/mec.17774. Epub 2025 Apr 25.
5
Epigenetic Echoes: Bridging Nature, Nurture, and Healing Across Generations.表观遗传回声：跨越世代连接天性、教养与治愈。
Int J Mol Sci. 2025 Mar 27;26(7):3075. doi: 10.3390/ijms26073075.
6
Analysis of Hepatic Lentiviral Vector Transduction: Implications for Preclinical Studies and Clinical Gene Therapy Protocols.肝内慢病毒载体转导分析：对临床前研究和临床基因治疗方案的启示。
Viruses. 2025 Feb 17;17(2):276. doi: 10.3390/v17020276.
7
The Effect of Bisphenol and Its Cytotoxicity on Female Infertility and Pregnancy Outcomes: A Narrative Review.双酚及其细胞毒性对女性不孕和妊娠结局的影响：一项叙述性综述
J Clin Med. 2024 Dec 12;13(24):7568. doi: 10.3390/jcm13247568.
8
Fundamentals of DNA methylation in development.发育过程中DNA甲基化的基本原理。
Pediatr Res. 2024 Dec 10. doi: 10.1038/s41390-024-03674-7.
9
Analysis of hepatic lentiviral vector transduction; implications for preclinical studies and clinical gene therapy protocols.肝内慢病毒载体转导分析；对临床前研究和临床基因治疗方案的影响。
bioRxiv. 2024 Aug 31:2024.08.20.608805. doi: 10.1101/2024.08.20.608805.
10
Dual Regulation Mechanism of Obesity: DNA Methylation and Intestinal Flora.肥胖的双重调节机制：DNA甲基化与肠道菌群
Biomedicines. 2024 Jul 23;12(8):1633. doi: 10.3390/biomedicines12081633.
本文引用的文献
1
Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development.孕期营养补充可抵消双酚A在早期发育过程中引起的DNA低甲基化。
Proc Natl Acad Sci U S A. 2007 Aug 7;104(32):13056-61. doi: 10.1073/pnas.0703739104. Epub 2007 Aug 1.
2
Environmental epigenomics and disease susceptibility.环境表观基因组学与疾病易感性
Nat Rev Genet. 2007 Apr;8(4):253-62. doi: 10.1038/nrg2045.
3
Epigenetics: a landscape takes shape.表观遗传学：一幅图景正在形成。
Cell. 2007 Feb 23;128(4):635-8. doi: 10.1016/j.cell.2007.02.006.
4
Transgenerational epigenetic imprinting of the male germline by endocrine disruptor exposure during gonadal sex determination.在性腺性别决定期间，内分泌干扰物暴露对雄性生殖系的跨代表观遗传印记。
Endocrinology. 2006 Dec;147(12):5524-41. doi: 10.1210/en.2006-0987. Epub 2006 Sep 14.
5
Maternal methyl supplements increase offspring DNA methylation at Axin Fused.母体甲基补充剂会增加子代Axin Fused基因处的DNA甲基化水平。
Genesis. 2006 Sep;44(9):401-6. doi: 10.1002/dvg.20230.
6
Dynamic reprogramming of DNA methylation at an epigenetically sensitive allele in mice.小鼠中一个表观遗传敏感等位基因处DNA甲基化的动态重编程
PLoS Genet. 2006 Apr;2(4):e49. doi: 10.1371/journal.pgen.0020049. Epub 2006 Apr 7.
7
Maternal genistein alters coat color and protects Avy mouse offspring from obesity by modifying the fetal epigenome.母体染料木黄酮通过改变胎儿表观基因组来改变毛色并保护Avy小鼠后代免于肥胖。
Environ Health Perspect. 2006 Apr;114(4):567-72. doi: 10.1289/ehp.8700.
8
Epigenetic transgenerational actions of endocrine disruptors and male fertility.内分泌干扰物的表观遗传跨代作用与男性生育能力
Science. 2005 Jun 3;308(5727):1466-9. doi: 10.1126/science.1108190.
9
Cellular and physiological effects of soy flavonoids.大豆黄酮的细胞和生理效应。
Mini Rev Med Chem. 2004 Oct;4(8):881-7. doi: 10.2174/1389557043403387.
10
Complex patterns of transcription at the insertion site of a retrotransposon in the mouse.小鼠中逆转录转座子插入位点处复杂的转录模式。
Nucleic Acids Res. 2004 Nov 1;32(19):5800-8. doi: 10.1093/nar/gkh914. Print 2004.
Zotero 插件