Salas Sironvalle M, Martín X, Gelet A, Sanseverino R, Marechal J M, Michel Dubernard J
Servicio de Urología, Hospital Edouard Herriot, Lyon, Francia.
Arch Esp Urol. 1991 Apr;44(3):273-80.
From 1984 to 1989, 15 patients with cystine calculi were treated by endourologic procedures and/or extracorporeal shock wave lithotripsy (ESWL). During this period the patients required 38 hospitalizations, a total of 74 calculi were treated localized to 61 sites: pelvic 21, caliceal 13 and 27 were multiple. The diagnosis was confirmed by a 24 hour cystinuria (3.595 muMol/24 h. average) and analysis of the stone fragments. Stone disruption was achieved in 17 of 38 cases (44.7%). ESWL as monotherapy was utilized in calculi less than 15-20 mm. in diameter; complete removal was achieved in of 18 cases. Percutaneous surgery (PC) was used alone or in combination with ESWL for large calculi or when ESWL failed to achieve stone fragmentation. Complete stones removal was achieved in 5 of 9 cases using PC as monotherapy and in 5 of 10 in combination with ESWL. There were 23 recurrences during this period; 13 patients with residual stone fragments and 10 patients that were stone-free. The present study reports our experience in the treatment of cystine calculi by PC and/or ESWL and the long-term results achieved with the respective treatment modalities.
1984年至1989年期间,15例胱氨酸结石患者接受了腔内泌尿外科手术和/或体外冲击波碎石术(ESWL)治疗。在此期间,这些患者共住院38次,共治疗了74颗结石,结石位于61个部位:肾盂21处,肾盏13处,27处为多发。通过24小时尿胱氨酸测定(平均3.595μMol/24小时)和结石碎片分析确诊。38例中有17例(44.7%)实现了结石破碎。直径小于15 - 20毫米的结石采用ESWL单一疗法;18例实现了结石完全清除。经皮手术(PC)单独或与ESWL联合用于治疗较大结石或ESWL未能使结石破碎的情况。PC单一疗法治疗的9例中有5例实现了结石完全清除,与ESWL联合治疗的10例中有5例实现了结石完全清除。在此期间有23例复发;13例有残留结石碎片,10例结石已清除。本研究报告了我们采用PC和/或ESWL治疗胱氨酸结石的经验以及各自治疗方式所取得的长期结果。